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替硝唑与多西环素联合用于胃肠手术的短期化疗预防

Combined tinidazole and doxycycline short term chemotherapeutic prophylaxis in gastro-intestinal surgery.

作者信息

Giercksky K E, Christiansen E, Berge L, Fuglesang J, Johnson J A

出版信息

Scand J Gastroenterol Suppl. 1980;59:41-4.

PMID:6988950
Abstract

Infectious complications following gastro-intestinal surgery can be reduced with properly administered antimicrobial agents. One single preoperative dose of doxycyline (200 mg) and tinidazole (2 g) gave a highly significant reduction of infectious complications in a controlled clinical study of 307 patients undergoing elective gastro-intestinal surgery.

摘要

通过合理使用抗菌药物,可减少胃肠道手术后的感染并发症。在一项针对307例接受择期胃肠道手术患者的对照临床研究中,术前单次给予强力霉素(200毫克)和替硝唑(2克)能显著降低感染并发症的发生率。

相似文献

1
Combined tinidazole and doxycycline short term chemotherapeutic prophylaxis in gastro-intestinal surgery.替硝唑与多西环素联合用于胃肠手术的短期化疗预防
Scand J Gastroenterol Suppl. 1980;59:41-4.
2
Tinidazole and doxycycline compared to doxycycline alone as prophylactic antimicrobial agents in elective colorectal surgery.替硝唑与多西环素联用与单用多西环素作为择期结直肠手术预防性抗菌药物的比较。
Scand J Gastroenterol Suppl. 1980;59:21-4.
3
Combined tinidazole and doxycycline prophylaxis in colorectal surgery. An interhospital trial.结直肠手术中替硝唑与多西环素联合预防性用药:一项医院间试验
Scand J Gastroenterol Suppl. 1980;59:25-8.
4
Tinidazole and doxycycline as antimicrobials in elective colorectal surgery. A randomized multicentre trial.替硝唑和多西环素作为择期结直肠手术中的抗菌药物。一项随机多中心试验。
Scand J Gastroenterol Suppl. 1980;59:29-35.
5
The value of the prophylactic use of doxycycline and tinidazole in elective colorectal surgery.
Scand J Gastroenterol Suppl. 1980;59:17-20.
6
Should antimicrobial prophylaxis in colorectal surgery include agents effective against both anaerobic and aerobic microorganisms? A double-blind, multicenter study. The Norwegian Study Group for Colorectal Surgery.结直肠手术中的抗菌预防措施是否应包括对厌氧和需氧微生物均有效的药物?一项双盲、多中心研究。挪威结直肠外科学术研究小组
Surgery. 1985 Apr;97(4):402-8.
7
Symposium on chemotherapeutic prophylaxis in colo-rectal surgery.结直肠手术中化疗预防研讨会
Scand J Gastroenterol Suppl. 1980;59:1-44.
8
Systemic prophylaxis in colorectal surgery a comparison between tinidazole and doxycycline.
Scand J Infect Dis Suppl. 1981;26:75-8.
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Clinical trial of prophylaxis of wound sepsis in elective colorectal surgery comparing ticarcillin with tinidazole. University of Melbourne Colorectal Group.在择期结直肠手术中比较替卡西林与替硝唑预防伤口脓毒症的临床试验。墨尔本大学结直肠研究小组。
Aust N Z J Surg. 1986 Mar;56(3):209-13.
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Tinidazole prophylaxis in appendicectomies. A controlled study of single-dose versus 3-day therapy.替硝唑在阑尾切除术中的预防作用。单剂量与3天疗法的对照研究。
Scand J Gastroenterol. 1984 Jan;19(1):111-5.

引用本文的文献

1
Tinidazole in anaerobic infections: a review of its antibacterial activity, pharmacological properties and therapeutic efficacy.替硝唑在厌氧菌感染中的应用:抗菌活性、药理特性及治疗效果综述
Drugs. 1982 Aug;24(2):85-117. doi: 10.2165/00003495-198224020-00001.
2
Tinidazole--microbiology, pharmacology and efficacy in anaerobic infections.
Infection. 1983 Jan-Feb;11(1):54-60. doi: 10.1007/BF01651361.