Giercksky K E, Christiansen E, Berge L, Fuglesang J, Johnson J A
Scand J Gastroenterol Suppl. 1980;59:41-4.
Infectious complications following gastro-intestinal surgery can be reduced with properly administered antimicrobial agents. One single preoperative dose of doxycyline (200 mg) and tinidazole (2 g) gave a highly significant reduction of infectious complications in a controlled clinical study of 307 patients undergoing elective gastro-intestinal surgery.
通过合理使用抗菌药物,可减少胃肠道手术后的感染并发症。在一项针对307例接受择期胃肠道手术患者的对照临床研究中,术前单次给予强力霉素(200毫克)和替硝唑(2克)能显著降低感染并发症的发生率。