Procedures for screening chemicals for carcinogenicity.
作者信息
Purchase I F
出版信息
Br J Ind Med. 1980 Feb;37(1):1-10. doi: 10.1136/oem.37.1.1.
Abstract
摘要
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Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.致癌物是诱变剂：一种将用于活化的肝脏匀浆和用于检测的细菌相结合的简单测试系统。
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3
Tissue-mediated mutagenicity of vinylidene chloride and 2-chlorobutadiene in Salmonella typhimurium.
Nature. 1975 Jun 19;255(5510):641-3. doi: 10.1038/255641a0.
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Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.在沙门氏菌/微粒体试验中作为诱变剂的致癌物检测：300种化学物质的测定
Proc Natl Acad Sci U S A. 1975 Dec;72(12):5135-9. doi: 10.1073/pnas.72.12.5135.
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The utilization of in vitro mutagenesis techniques to explain strain, age and sex related differences in dimethylnitrosamine tumor susceptibilities in mice.利用体外诱变技术解释小鼠中二甲基亚硝胺肿瘤易感性的品系、年龄和性别相关差异。
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7
Comparative mutagenicity of N-nitrosamines in a semi-solid and in a liquid incubation system in the presence of rat or human tissue fractions.在大鼠或人体组织成分存在的情况下，N-亚硝胺在半固体和液体培养系统中的比较诱变性。
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Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.用沙门氏菌/哺乳动物微粒体诱变性试验检测致癌物和诱变剂的方法。
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Mutagenicity of azathioprine.
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