Speck W T, Rosenkranz H S
Cancer Res. 1976 Jan;36(1):108-9.
Azathioprine (6-[(1-methyl-4-nitroimidazol-5-yl)thio]purine; lmuran) is mutagenic for Salmonella typhirmuium. Demonstration of this mutagenic effect requires a period of anaerobic incubation of the bacteria with the test agent.
硫唑嘌呤(6-[(1-甲基-4-硝基咪唑-5-基)硫代]嘌呤;依木兰)对鼠伤寒沙门氏菌具有致突变性。要证明这种致突变作用,需要将细菌与受试物进行一段厌氧培养时间。