Griffin N K, Spanos A, Jenkins P A, Turner R C, Werther G, Baum J D
Arch Dis Child. 1980 Feb;55(2):112-7. doi: 10.1136/adc.55.2.112.
15 metabolic profiles were performed on 10 diabetic children who were on once-daily injections of insulin. Blood and urine glucose concentrations were high throughout much of the day and night, and were associated with abnormal levels of blood ketones, lactate, and pyruvate. The plasma free-insulin profiles gave a characteristic pattern for each type of insulin. The investigation gives valuable information for the clinical management of such children.
对10名每日注射一次胰岛素的糖尿病儿童进行了15次代谢谱分析。在白天和夜间的大部分时间里,血糖和尿糖浓度都很高,并且与血液中酮体、乳酸和丙酮酸的异常水平有关。每种胰岛素的血浆游离胰岛素谱都呈现出一种特征性模式。该研究为这类儿童的临床管理提供了有价值的信息。