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Insulin-lecithin interaction in non-aqueous solvents and its change after application of a static electric field.

作者信息

Galzigna L, Garbin L, Rigoni F, Siliprandi N

出版信息

Mol Cell Biochem. 1980 Mar 20;30(1):3-6. doi: 10.1007/BF00215300.

DOI:10.1007/BF00215300
PMID:6991910
Abstract

The interaction between dipalmitoyl lecithin and egg lecithin with insulin was studied in a non-aqueous solvent such as dioxane-chloroform (1:1) by dielectric constant measurements and absorption spectra. The electrostatic character of the interaction results from the dielectric measurements and the effect of an external application of a static electric field (F = 30 kV/cm) is apparently related to the strength of such an interaction. The different strength of interaction of insulin with the two types of lecithins results also from experiments with a two-phase system.

摘要

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本文引用的文献

1
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2
Molecular species of lecithins from erythrocytes and plasma of man.
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Physical studies on proinsulin-association behavior and conformation in solution.胰岛素原在溶液中的缔合行为及构象的物理研究。
Biochem Biophys Res Commun. 1968 Jul 26;32(2):155-60. doi: 10.1016/0006-291x(68)90362-8.
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Lecithin-protein interaction in the GTP-dependent acyl-CoA synthase.
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The interaction of insulin with phospholipids.胰岛素与磷脂的相互作用。
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Dipole moment of acetylcholine and its relevance to the chemical synaptic transmission.乙酰胆碱的偶极矩及其与化学突触传递的相关性。
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7
Dielectric increment of low molecular weight RNA in dioxane after application of static electric fields.施加静电场后低分子量RNA在二氧六环中的介电增量。
Biochim Biophys Acta. 1976 Oct 4;447(2):230-7. doi: 10.1016/0005-2787(76)90345-2.