Gürtler B A
Schweiz Med Wochenschr. 1977 Oct 29;107(43):1537-41.
The distinction between upper and lower urinary tract infection (UTI) is of great help in the management and treatment of these conditions. The antibody-coating technique was used to investigate urine of patients with nephrostomies, chronic and acute pyelonephritis, chronic and acute cystitis, of male patients with dysuria and significant bacteriuria and of female patients with indwelling catheters. Furthermore this indirect method was compared with FAIRLEY'S direct method for localization of UTI in female patients with indwelling catheters. All tests were positive in patients with nephrostomies and acute pyelonephritis. Out of 19 tests in patients with chronic pyelonephritis, 18 were positive and one negative. Antibody-coated bacteria were present in 4 out of 8 patients with chronic cystitis and in 2 out of 9 patients with acute cystitis. Out of 5 male patients with dysuria and significant bacteriuria, 3 had a positive test. Out of 25 women with indwelling catheters 20 exhibited antibody-coated bacteria in urine and 5 did not. In 9 female patients with indwelling catheters the UTI was localized in the upper tract 5 times by the Fairley technique but 7 times by determination of antibody-coated bacteria. The demonstration of antibody-coated bacteria in the urine is a simple and reliable method of localizing the site of a UTI. False positive results may be observed in patients with indwelling catheters and prostatitis; in both instances there is probably local antibody production and coating of the bacteria. As the test is relatively expensive and time-consuming, it is indicated only in special situations and is not considered a routine screening procedure.
上、下尿路感染（UTI）的区分对这些病症的管理和治疗有很大帮助。采用抗体包被技术对肾造口术患者、急慢性肾盂肾炎患者、急慢性膀胱炎患者、排尿困难且菌尿显著的男性患者以及留置导尿管的女性患者的尿液进行研究。此外，还将这种间接方法与费尔利（FAIRLEY）用于留置导尿管女性患者UTI定位的直接方法进行了比较。所有肾造口术患者和急性肾盂肾炎患者的检测均呈阳性。在慢性肾盂肾炎患者的19次检测中，18次呈阳性，1次呈阴性。8例慢性膀胱炎患者中有4例以及9例急性膀胱炎患者中有2例存在抗体包被细菌。在5例排尿困难且菌尿显著的男性患者中，3例检测呈阳性。在25例留置导尿管的女性患者中，20例尿液中出现抗体包被细菌，5例未出现。在9例留置导尿管的女性患者中，费尔利技术将UTI定位在上尿路5次，而通过检测抗体包被细菌定位7次。尿液中抗体包被细菌的检测是一种简单且可靠的UTI定位方法。在留置导尿管患者和前列腺炎患者中可能会出现假阳性结果；在这两种情况下，可能都存在局部抗体产生和细菌包被现象。由于该检测相对昂贵且耗时，仅在特殊情况下使用，不被视为常规筛查程序。
