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在大型妇科手术中使用替硝唑进行化学预防。

Chemoprophylaxis with tinidazole in major gynaecological surgery.

作者信息

Kuhn R J

出版信息

Aust N Z J Obstet Gynaecol. 1980 Feb;20(1):43-6. doi: 10.1111/j.1479-828x.1980.tb00894.x.

DOI:10.1111/j.1479-828x.1980.tb00894.x
PMID:6992764
Abstract

A double-blind trial involving 200 patients failed to show a statistically significant reduction in postoperative pelvic infection with tinidazole chemoprophylaxis. Preoperative and postoperative cervical or vaginal bacteriological swabs and full blood counts did not contribute to management. Drains to the vaginal vault were not associated with a reduction in this complication. The incidence of postoperative pelvic sepsis was also unrelated to the experience of the surgeon.

摘要

一项涉及200名患者的双盲试验未能显示替硝唑预防性化疗在术后盆腔感染方面有统计学上的显著降低。术前和术后的宫颈或阴道细菌学拭子检查及全血细胞计数对治疗并无帮助。阴道穹窿引流与该并发症的减少无关。术后盆腔脓毒症的发生率也与外科医生的经验无关。

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引用本文的文献

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Tinidazole in anaerobic infections: a review of its antibacterial activity, pharmacological properties and therapeutic efficacy.替硝唑在厌氧菌感染中的应用:抗菌活性、药理特性及治疗效果综述
Drugs. 1982 Aug;24(2):85-117. doi: 10.2165/00003495-198224020-00001.