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The practical benefits of pharmacokinetics in the use of antineoplastic agents.

作者信息

Erlichman C, Donehower R C, Chabner B A

出版信息

Cancer Chemother Pharmacol. 1980;4(3):139-45. doi: 10.1007/BF00254011.

DOI:10.1007/BF00254011
PMID:6994913
Abstract
摘要

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本文引用的文献

1
THE PHYSIOLOGIC DISPOSITION OF 5-FLUOROURACIL AND 5-FLUORO-2'-DEOXYURIDINE IN MAN.
Clin Pharmacol Ther. 1964 Sep-Oct;5:581-610. doi: 10.1002/cpt196455581.
2
The role of phosphopyridinenucleotides in the metabolism of cortisol by peripheral tissue.磷酸吡啶核苷酸在周围组织皮质醇代谢中的作用。
Biochim Biophys Acta. 1960 Nov 4;44:217-23. doi: 10.1016/0006-3002(60)91556-0.
3
Phase I and pharmacological studies of 5-fluorouracil administered intraperitoneally.5-氟尿嘧啶腹腔注射的I期及药理学研究
Clinical pharmacokinetics of commonly used anticancer drugs.
常用抗癌药物的临床药代动力学
Clin Pharmacokinet. 1983 May-Jun;8(3):202-32. doi: 10.2165/00003088-198308030-00002.
5
Intrahepatic and intravenous administration of adriamycin--a comparative pharmacokinetic study in patients with malignant liver tumours.阿霉素肝内与静脉内给药——恶性肝肿瘤患者的比较药代动力学研究
Med Oncol Tumor Pharmacother. 1985;2(1):47-54. doi: 10.1007/BF02934780.
6
Pharmacokinetics and toxicity of the epipodophyllotoxin derivative etoposide (VP 16-213) in patients with gestational choriocarcinoma and malignant teratoma.
Cancer Chemother Pharmacol. 1985;15(1):66-71. doi: 10.1007/BF00257298.
7
Variability of tumor response to chemotherapy. I. Contribution of host heterogeneity.
Cancer Chemother Pharmacol. 1987;20(4):297-304. doi: 10.1007/BF00262580.
8
Therapeutic drug monitoring in oncology. Problems and potential in antineoplastic therapy.肿瘤学中的治疗药物监测。抗肿瘤治疗中的问题与潜力。
Clin Pharmacokinet. 1987 Oct;13(4):205-27. doi: 10.2165/00003088-198713040-00001.
Cancer Res. 1980 Mar;40(3):567-72.
4
Methotrexate toxicity: correlation with duration of administration, plasma levels, dose and excretion pattern.甲氨蝶呤毒性：与给药持续时间、血浆水平、剂量及排泄模式的相关性
Eur J Cancer (1965). 1972 Aug;8(4):409-14. doi: 10.1016/0014-2964(72)90125-9.
5
The physiological disposition of the carcinostatic 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in man and animals.抗癌药1,3-双（2-氯乙基）-1-亚硝基脲（卡莫司汀）在人和动物体内的生理分布。
Clin Pharmacol Ther. 1967 Jul-Aug;8(4):566-77. doi: 10.1002/cpt196784566.
6
Adriamycin chemotherapy--efficacy, safety, and pharmacologic basis of an intermittent single high-dosage schedule.阿霉素化疗——间歇性单次高剂量方案的疗效、安全性及药理学基础
Cancer. 1974 Jan;33(1):19-27. doi: 10.1002/1097-0142(197401)33:1<19::aid-cncr2820330107>3.0.co;2-m.
7
The administration of 5-fluorouracil by mouth.口服5-氟尿嘧啶。
Cancer. 1974 Jan;33(1):14-8. doi: 10.1002/1097-0142(197401)33:1<14::aid-cncr2820330106>3.0.co;2-3.
8
Threshold methotrexate concentration for in vivo inhibition of DNA synthesis in normal and tumorous target tissues.甲氨蝶呤在体内抑制正常和肿瘤靶组织中DNA合成的阈值浓度。
J Clin Invest. 1973 Aug;52(8):1804-11. doi: 10.1172/JCI107362.
9
GLC assay for 5-fluorouracil in biological fluids.生物流体中5-氟尿嘧啶的葡萄糖醛酸苷测定法。
J Pharm Sci. 1973 Apr;62(4):572-5. doi: 10.1002/jps.2600620405.
10
Clinical pharmacology of oral and intravenous 5-fluorouracil (NSC-19893).
Cancer Chemother Rep. 1974 Sep-Oct;58(5 Pt 1):723-31.