• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Activation of the alternative pathway of complement by mycobacteria and cord factor.分枝杆菌与索状因子对补体替代途径的激活作用。
Infect Immun. 1980 Jul;29(1):30-5. doi: 10.1128/iai.29.1.30-35.1980.
2
Brucella abortus vaccines: comparison of protection provided by immunopotentiated 45/20 bacterins and live strain 19 vaccine in guinea pigs.牛种布鲁氏菌疫苗：免疫增强45/20菌苗和19号活疫苗在豚鼠中提供的保护作用比较
Am J Vet Res. 1981 Nov;42(11):1959-62.
3
Elimination of Mycobacterium leprae subsequent to local in vivo activation of macrophages in lepromatous leprosy by other mycobacteria.在瘤型麻风病中，其他分枝杆菌在体内局部激活巨噬细胞后麻风分枝杆菌的清除。
Clin Exp Immunol. 1974 Jun;17(2):261-5.
4
Comparison of muramyl dipeptide, trehalose dimycolate, and dimethyl dioctadecyl ammonium bromide as adjuvants in Brucella abortus 45/20 vaccines.布鲁氏菌45/20疫苗中胞壁酰二肽、海藻糖二霉菌酸酯和二甲基二十八烷基溴化铵作为佐剂的比较。
Infect Immun. 1980 Nov;30(2):409-12. doi: 10.1128/iai.30.2.409-412.1980.
5
Human phagocyte respiratory burst by Mycobacterium bovis BCG and M. leprae: functional activation by BCG is mediated by complement and its receptors on monocytes.牛分枝杆菌卡介苗（BCG）和麻风分枝杆菌引发的人类吞噬细胞呼吸爆发：BCG的功能激活由补体及其在单核细胞上的受体介导。
Int J Lepr Other Mycobact Dis. 1992 Jun;60(2):225-33.
6
Activation of the human complement system by phenolic glycolipid 1 of Mycobacterium leprae.麻风分枝杆菌酚糖脂1对人补体系统的激活作用。
Microb Pathog. 1990 Jun;8(6):403-10. doi: 10.1016/0882-4010(90)90027-n.
7
A role for natural antibody in the pathogenesis of leprosy: antibody in nonimmune serum mediates C3 fixation to the Mycobacterium leprae surface and hence phagocytosis by human mononuclear phagocytes.天然抗体在麻风病发病机制中的作用：非免疫血清中的抗体介导补体C3固定于麻风杆菌表面，进而被人单核吞噬细胞吞噬。
Infect Immun. 1994 Jan;62(1):280-9. doi: 10.1128/iai.62.1.280-289.1994.
8
Protective effect of muramyl dipeptide analogs in combination with trehalose dimycolate against aerogenic influenza virus and Mycobacterium tuberculosis infections in mice.胞壁酰二肽类似物与海藻糖二霉菌酸酯联合使用对小鼠气源性流感病毒和结核分枝杆菌感染的保护作用。
J Biol Response Mod. 1984 Dec;3(6):663-71.
9
A macrophage invasion mechanism of pathogenic mycobacteria.致病性分枝杆菌的巨噬细胞侵袭机制。
Science. 1997 Aug 22;277(5329):1091-3. doi: 10.1126/science.277.5329.1091.
10
[Chemical synthesis and immunologic activities of the active unit of BCG-CWS].
Nihon Rinsho. 1981 Apr;39(4):1861-7.

引用本文的文献

1
Innate Immune Pattern Recognition Receptors of Mycobacterium tuberculosis: Nature and Consequences for Pathogenesis of Tuberculosis.结核分枝杆菌固有免疫模式识别受体：性质及其对结核病发病机制的影响。
Adv Exp Med Biol. 2021;1313:179-215. doi: 10.1007/978-3-030-67452-6_9.
2
Human Properdin Modulates Macrophage: BCG Interaction Thrombospondin Repeats 4 and 5.人补体因子 P 调节巨噬细胞：卡介苗相互作用 血栓反应蛋白重复 4 和 5。
Front Immunol. 2018 May 8;9:533. doi: 10.3389/fimmu.2018.00533. eCollection 2018.
3
Decreased C3 Activation by the devR Gene-Disrupted Mycobacterium tuberculosis Strain in Comparison to the Wild-Type Strain.与野生型菌株相比，devR基因缺失的结核分枝杆菌菌株的C3激活减少。
Int J Bacteriol. 2013;2013:512481. doi: 10.1155/2013/512481. Epub 2013 May 18.
4
Activation of the classical complement pathway by Bacillus anthracis is the primary mechanism for spore phagocytosis and involves the spore surface protein BclA.炭疽杆菌通过经典补体途径的激活是孢子吞噬的主要机制，涉及孢子表面蛋白 BclA。
J Immunol. 2012 May 1;188(9):4421-31. doi: 10.4049/jimmunol.1102092. Epub 2012 Mar 21.
5
A role for tumour necrosis factor-alpha, complement C5 and interleukin-6 in the initiation and development of the mycobacterial cord factor trehalose 6,6'-dimycolate induced granulomatous response.肿瘤坏死因子-α、补体C5和白细胞介素-6在分枝杆菌索状因子海藻糖6,6'-二霉菌酸诱导的肉芽肿反应的起始和发展中的作用。
Microbiology (Reading). 2008 Jun;154(Pt 6):1813-1824. doi: 10.1099/mic.0.2008/016923-0.
6
Complement protein C3 binding to Mycobacterium tuberculosis is initiated by the classical pathway in human bronchoalveolar lavage fluid.在人支气管肺泡灌洗液中，补体蛋白C3与结核分枝杆菌的结合是由经典途径启动的。
Infect Immun. 2004 May;72(5):2564-73. doi: 10.1128/IAI.72.5.2564-2573.2004.
7
Interstitial and hemorrhagic pneumonitis induced by mycobacterial trehalose dimycolate.分枝杆菌海藻糖二霉菌酸酯诱导的间质性和出血性肺炎。
Am J Pathol. 1982 Mar;106(3):348-55.
8
Interactions of killed Listeria monocytogenes with the mouse complement system.灭活单核细胞增生李斯特菌与小鼠补体系统的相互作用。
Infect Immun. 1981 Oct;34(1):16-9. doi: 10.1128/iai.34.1.16-19.1981.
9
Reduced complement-mediated immune complex solubilization in leprosy patients.麻风病患者中补体介导的免疫复合物溶解减少。
Clin Exp Immunol. 1985 Jun;60(3):553-8.
10
Activation of rat alveolar macrophages and protection against i.v. injected tumor cells by intratracheal administration of trehalose dimycolate.通过气管内给予海藻糖二霉菌酸酯激活大鼠肺泡巨噬细胞并保护其免受静脉注射肿瘤细胞的侵害。
Cancer Immunol Immunother. 1986;23(3):200-6. doi: 10.1007/BF00205650.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Preparation and properties of a freeze-dried B.C.G. vaccine of increased stability.一种稳定性增强的冻干卡介苗疫苗的制备及特性
Br Med J. 1962 Oct 27;2(5312):1086-9. doi: 10.1136/bmj.2.5312.1086.
3
Effect of macrocyclon in acute and chronic pulmonary tuberculous infection in mice as shown by viable and total bacterial counts.通过活菌计数和总细菌计数显示大环内酯对小鼠急性和慢性肺结核感染的影响。
Br J Exp Pathol. 1960 Aug;41(4):414-21.
4
Experimental design for bioassay of a material inducing strong tachyphylactic effect (anaphylatoxin).诱导强烈快速耐受性效应（过敏毒素）物质生物测定的实验设计。
Br J Pharmacol Chemother. 1956 Sep;11(3):252-62. doi: 10.1111/j.1476-5381.1956.tb01063.x.
5
Properdin system and immunity. II. Interaction of the properdin system with polysaccharides.备解素系统与免疫。II. 备解素系统与多糖的相互作用。
Science. 1955 Sep 23;122(3169):545-9. doi: 10.1126/science.122.3169.545.
6
Multiple nature of the third component of guinea-pig complement. I. Separation and characterization of three factors a, b, and c, essential for haemolysis.豚鼠补体第三成分的多重性质。I. 溶血所必需的三种因子a、b和c的分离与特性鉴定。
Immunology. 1965 Jun;8(6):590-603.
7
Independent and consecutive action of the complement components C5, C6 and C7 in immune hemolysis. I. Preparation of EAC1-5 with purified guinea pig C3 and C5.补体成分C5、C6和C7在免疫溶血中的独立连续作用。I. 用纯化的豚鼠C3和C5制备EAC1-5 。
Immunochemistry. 1970 Dec;7(12):955-65. doi: 10.1016/0019-2791(70)90002-9.
8
C3 shunt activation in human serum chelated with EGTA.在与乙二醇双四乙酸螯合的人血清中C3旁路激活。
J Immunol. 1972 Oct;109(4):807-9.
9
Interaction of complement and polymyxin with gram-negative bacteria.补体与多粘菌素与革兰氏阴性菌的相互作用。
Infect Immun. 1972 Nov;6(5):709-17. doi: 10.1128/iai.6.5.709-717.1972.
10
The walls of Mycobacterium lepraemurium: chemistry and ultrastructure.
J Gen Microbiol. 1971 Dec;69(3):313-24. doi: 10.1099/00221287-69-3-313.

分枝杆菌与索状因子对补体替代途径的激活作用。

Activation of the alternative pathway of complement by mycobacteria and cord factor.

作者信息

Ramanathan V D, Curtis J, Turk J L

出版信息

Infect Immun. 1980 Jul;29(1):30-5. doi: 10.1128/iai.29.1.30-35.1980.

DOI:10.1128/iai.29.1.30-35.1980
PMID:6995341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC551070/
Abstract

The ability of a number of mycobacteria and some of their components to activate complement was examined. Mycobacterium bovis BCG (Glaxo strain), Mycobacterium leprae, Mycobacterium lepraemurium, and cord factor activated the alternative pathway of complement in normal human serum and normal and C4-deficient guinea pig sera and generated biologically active products. BCG (Pasteur strain) and muramyl dipeptide did not activate complement. The relevance of activation of complement by mycobacteria to their induction of granulomas is discussed.

摘要

研究了多种分枝杆菌及其某些成分激活补体的能力。牛型结核分枝杆菌卡介苗（葛兰素株）、麻风分枝杆菌、鼠麻风分枝杆菌和索状因子可激活正常人血清以及正常和C4缺陷豚鼠血清中的补体替代途径，并产生生物活性产物。卡介苗（巴斯德株）和胞壁酰二肽不能激活补体。讨论了分枝杆菌激活补体与其诱导肉芽肿之间的相关性。