Pasnick M, Mead P B, Philip A G
Am J Obstet Gynecol. 1980 Nov 1;138(5):480-4. doi: 10.1016/0002-9378(80)90273-2.
During a 5-year period vaginal cultures were obtained from all women with an obstetric history of premature onset of labor or premature rupture of membranes. With these indications, 1,213 (12.7%) of all parturient patients were cultured and 10.2% of those cultured were colonized with group B beta-hemolytic streptococci. Maternal colonization did not correlate with ABO blood group, although a significantly higher percentage of Rh negative women were colonized (p < 0.01). During this 5-year period, 20 infants had documented early-onset infection (sepsis or meningitis) with group B beta-hemolytic streptococci. All 10 infants had a maternal history of premature onset of labor and/or premature rupture of membranes. Mothers of eight infants were cultured and seven of these cultures were positive. Approximately one of every 20 infants designated at high risk actually developed early-onset disease. Selective maternal culturing effectively identifies those infants as risk for early-onset group B streptococcal disease.
在5年期间，对所有有早产或胎膜早破产科病史的妇女进行了阴道培养。基于这些指征，对所有产妇中的1213例（12.7%）进行了培养，其中10.2%的培养对象被B族β溶血性链球菌定植。产妇定植情况与ABO血型无关，尽管Rh阴性妇女的定植比例显著更高（p<0.01）。在这5年期间，有20例婴儿记录有B族β溶血性链球菌早发型感染（败血症或脑膜炎）。所有10例婴儿的母亲均有早产和/或胎膜早破病史。对8例婴儿的母亲进行了培养，其中7例培养结果为阳性。每20名被指定为高危的婴儿中约有1名实际发生了早发型疾病。选择性产妇培养有效地识别出那些有早发型B族链球菌疾病风险的婴儿。
