用于检测孕妇B族链球菌的快速筛查试验评估
Evaluation of a rapid screening test for detecting group B streptococci in pregnant women.
作者信息
Granato P A, Petosa M T
机构信息
Department of Pathology, Crouse Irving Memorial Hospital, Syracuse, New York 13210.
出版信息
J Clin Microbiol. 1991 Jul;29(7):1536-8. doi: 10.1128/jcm.29.7.1536-1538.1991.
Abstract
The QUIDEL Group B Strep Test is an enzyme immunoassay (EIA) that was compared with culture for the rapid detection of moderate to high levels of group B streptococci (GBS) colonization in pregnant women. A total of 331 pregnant women were included in the study protocol, and GBS were cultured from 19 of these patients in moderate or greater amounts (incidence of 5.7%). Compared with culture, the EIA had a sensitivity, specificity, and positive and negative predictive values of 89, 99, 89, and 99%, respectively. With a sensitivity of 89%, the 95% confidence interval for this assay is 88 to 90%. The QUIDEL EIA test can be performed in less than 10 min and appears to be a reliable method for detecting moderate or greater amounts of GBS in vaginal or cervical specimens.
摘要
QUIDEL B族链球菌检测是一种酶免疫测定法（EIA），该方法与培养法进行了比较，用于快速检测孕妇中中高水平的B族链球菌（GBS）定植情况。共有331名孕妇纳入研究方案，其中19名患者培养出中等或更多数量的GBS（发生率为5.7%）。与培养法相比，该酶免疫测定法的敏感性、特异性、阳性预测值和阴性预测值分别为89%、99%、89%和99%。该检测方法敏感性为89%，其95%置信区间为88%至90%。QUIDEL酶免疫测定法检测可在不到10分钟内完成，似乎是检测阴道或宫颈标本中中等或更多数量GBS的可靠方法。
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本文引用的文献
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