• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

鸡主要组织相容性抗原与疱疹病毒诱导的淋巴瘤细胞表面肿瘤相关抗原的独立性

Independence of chicken major histocompatibility antigens and tumor-associated antigen on the surface of herpesvirus-induced lymphoma cells.

作者信息

Coleman R M, Schierman L W

出版信息

Infect Immun. 1980 Sep;29(3):1067-72. doi: 10.1128/iai.29.3.1067-1072.1980.

DOI:10.1128/iai.29.3.1067-1072.1980
PMID:7000703
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC551240/
Abstract

Capping of chicken major histocompatibility (MHC) antigens on normal thymus, spleen, and peripheral blood leukocytes was demonstrated, although MHC antigens appeared to be present on only 15 to 18% of normal thymus cells. MHC antigen capping also occurred on cells from a Marek's disease herpesvirus-induced transplantable lymphoma (MDCT-NYM1). Capping of a Marek's disease tumor-associated surface antigen (MATSA) could be induced on MDCT-NYM1 lymphoma cells as well as on cells of two Marek's disease in vitro lymphoblastoid cell lines (MDCC-MSB1 and MDCC-LS1). Cocapping of MHC antigens and MATSA did not occur on MDCT-NYM1 lymphoma cells. The results suggest that MHC antigens and MATSA are not structurally associated on the cell membrane.

摘要

已证实鸡主要组织相容性（MHC）抗原在正常胸腺、脾脏和外周血白细胞上会形成帽状结构，尽管MHC抗原似乎仅存在于15%至18%的正常胸腺细胞上。MHC抗原帽状结构也出现在马立克氏病疱疹病毒诱导的可移植淋巴瘤（MDCT-NYM1）的细胞上。马立克氏病肿瘤相关表面抗原（MATSA）的帽状结构可在MDCT-NYM1淋巴瘤细胞以及两种马立克氏病体外淋巴母细胞系（MDCC-MSB1和MDCC-LS1）的细胞上诱导形成。MHC抗原和MATSA在MDCT-NYM1淋巴瘤细胞上不会共同形成帽状结构。结果表明，MHC抗原和MATSA在细胞膜上没有结构关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e23/551240/89e37a5652d7/iai00177-0234-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e23/551240/014e2f12f920/iai00177-0233-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e23/551240/45e86f4aca16/iai00177-0234-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e23/551240/89e37a5652d7/iai00177-0234-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e23/551240/014e2f12f920/iai00177-0233-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e23/551240/45e86f4aca16/iai00177-0234-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e23/551240/89e37a5652d7/iai00177-0234-b.jpg

相似文献

1
Independence of chicken major histocompatibility antigens and tumor-associated antigen on the surface of herpesvirus-induced lymphoma cells.鸡主要组织相容性抗原与疱疹病毒诱导的淋巴瘤细胞表面肿瘤相关抗原的独立性
Infect Immun. 1980 Sep;29(3):1067-72. doi: 10.1128/iai.29.3.1067-1072.1980.
2
Analysis of Marek's disease tumor-associated surface antigen on MDCC-MSB1-clo.18 cells.MDCC-MSB1-clo.18细胞上马立克氏病肿瘤相关表面抗原的分析
Int J Cancer. 1991 Jan 21;47(2):238-43. doi: 10.1002/ijc.2910470212.
3
Monoclonal antibody to chicken fetal antigen on Marek's disease lymphoblastoid cell line MDCC-MSB1.针对马立克氏病淋巴母细胞样细胞系MDCC-MSB1上鸡胎儿抗原的单克隆抗体。
Cancer Res. 1986 Nov;46(11):5858-63.
4
Demonstration of Marek's disease tumor-associated surface antigen in chickens infected with nononcogenic Marek's disease virus and herpesvirus of turkeys.在感染非致瘤性马立克氏病病毒和火鸡疱疹病毒的鸡中马立克氏病肿瘤相关表面抗原的展示。
J Natl Cancer Inst. 1978 Sep;61(3):855-7.
5
Development and characterization of a Marek's disease transplantable tumor in inbred line 72 chickens homozygous at the major (B) histocompatibility locus.在主要（B）组织相容性位点纯合的近交系72鸡中开发和鉴定马立克氏病可移植肿瘤。
Avian Dis. 1980 Apr-Jun;24(2):358-74.
6
Isolation of monoclonal antibodies reactive with Marek's disease tumor-associated surface antigen (MATSA).与马立克氏病肿瘤相关表面抗原（MATSA）反应的单克隆抗体的分离
Biken J. 1984 Dec;27(4):183-8.
7
Antibody directed against Marek's disease-associated tumor surface antigen can be eluted from Marek's disease tumor cells.针对马立克氏病相关肿瘤表面抗原的抗体可从马立克氏病肿瘤细胞中洗脱出来。
Vet Immunol Immunopathol. 1991 Sep;29(3-4):229-38. doi: 10.1016/0165-2427(91)90016-6.
8
Detection of a new antigen associated with chicken thrombocytes on Marek's disease lymphoblastoid cell line.在马立克氏病淋巴母细胞样细胞系上检测与鸡血小板相关的一种新抗原。
J Natl Cancer Inst. 1986 Jun;76(6):1085-94.
9
A nonproducer T lymphoblastoid cell line from Marek's disease transplantable tumor (JMV).一株源自马立克氏病可移植肿瘤（JMV）的非产生性T淋巴母细胞系。
Avian Dis. 1977 Jan-Mar;21(1):69-76.
10
Pathogenesis of Marek's disease: early appearance of Marek's disease tumor-associated surface antigen in infected chickens.马立克氏病的发病机制：感染鸡中马立克氏病肿瘤相关表面抗原的早期出现。
J Natl Cancer Inst. 1978 Sep;61(3):849-54.

本文引用的文献

1
In vitro cytotoxicity against Marek's disease lymphoblastoid cell lines after enzymatic removal of Marek's disease tumor-associated surface antigen.在酶促去除马立克氏病肿瘤相关表面抗原后，对马立克氏病淋巴母细胞系的体外细胞毒性。
J Virol. 1980 Apr;34(1):130-5. doi: 10.1128/JVI.34.1.130-135.1980.
2
Two cell lines from lymphomas of Marek's disease.来自马立克氏病淋巴瘤的两个细胞系。
Biken J. 1974 Sep;17(3):105-16.
3
Hybrid antibody-induced topographical redistribution of surface immunoglobulins, alloantigens, and concanavalin A receptors on mouse lymphoid cells.
杂交抗体诱导小鼠淋巴细胞表面免疫球蛋白、同种异体抗原和伴刀豆球蛋白A受体的拓扑重分布。
Proc Natl Acad Sci U S A. 1974 Mar;71(3):932-6. doi: 10.1073/pnas.71.3.932.
4
Antibody-induced redistribution of HL-A antigens at the cell surface.抗体诱导的HL-A抗原在细胞表面的重新分布。
Eur J Immunol. 1972 Jun;2(3):249-57. doi: 10.1002/eji.1830020311.
5
Cell surface antigens of a mouse testicular teratoma. Identification of an antigen physically associated with H-2 antigens on tumor cells.小鼠睾丸畸胎瘤的细胞表面抗原。肿瘤细胞上与H-2抗原物理相关的一种抗原的鉴定。
J Exp Med. 1974 Jul 1;140(1):61-78. doi: 10.1084/jem.140.1.61.
6
Direct membrane immunofluorescence reaction of Burkitt's lymphoma cells in culture.培养的伯基特淋巴瘤细胞的直接膜免疫荧光反应。
Cancer Res. 1969 Apr;29(4):749-52.
7
Cellular immunity against Rous sarcomas of chickens. Preferential reactivity against autochthonous target cells as determined by lymphocyte adherence and cytotoxicity tests in vitro.鸡对劳斯肉瘤的细胞免疫。通过体外淋巴细胞黏附及细胞毒性试验确定对自身靶细胞的优先反应性。
Proc Natl Acad Sci U S A. 1974 Sep;71(9):3565-9. doi: 10.1073/pnas.71.9.3565.
8
Transplantation of a Marek's disease lymphoma in syngeneic chickens.同基因鸡中马立克氏病淋巴瘤的移植
J Immunol. 1974 Dec;113(6):1710-5.
9
Independence of H-2K and H-2D antigenic determinants on the surface of mouse lymphocytes.小鼠淋巴细胞表面H-2K和H-2D抗原决定簇的独立性
J Exp Med. 1973 Feb 1;137(2):511-26. doi: 10.1084/jem.137.2.511.
10
Functional interactions of viral and histocompatibility antigens at tumor cell surfaces.肿瘤细胞表面病毒抗原与组织相容性抗原的功能相互作用。
Proc Natl Acad Sci U S A. 1975 Dec;72(12):5066-70. doi: 10.1073/pnas.72.12.5066.