Sølling J, Sølling K, Lassen L
Scand J Rheumatol. 1980;9(2):118-22. doi: 10.3109/03009748009098140.
Immune complexes were detected by Clq-binding activity (Clq-BA) in 58% of 107 patients with seropositive rheumatoid arthritis (RA), and in 24% of 31 patients with seronegative arthritis. The difference is significant. Immune complexes were detected by the anticomplementarity test (AC) in approximately half of the patients without significant inter-group differences. No correlation was observed between the two methods. In 35 randomly selected patients with seropositive RA, a significant correlation was observed between Clq-BA and the functional class and the latex titre for rheumatoid factor. In patients with seronegative RA, the Clq-BA was significantly correlated to the number of joints with impaired mobility. The AC test was correlated to the erythrocyte sedimentation rate and the concentration of hemoglobin and gammaglobulin in patients with seropositive RA. As regards the clinical activity of disease, erythrocyte sedimentation rate and hemoglobin seem better parameters than the Clq-BA and AC tests.
通过Clq结合活性（Clq-BA）检测到，107例血清阳性类风湿性关节炎（RA）患者中有58%存在免疫复合物，31例血清阴性关节炎患者中有24%存在免疫复合物。差异具有显著性。通过抗补体试验（AC）在大约一半的患者中检测到免疫复合物，组间无显著差异。两种方法之间未观察到相关性。在35例随机选择的血清阳性RA患者中，观察到Clq-BA与类风湿因子的功能类别和乳胶滴度之间存在显著相关性。在血清阴性RA患者中，Clq-BA与活动受限关节的数量显著相关。在血清阳性RA患者中，AC试验与红细胞沉降率、血红蛋白浓度和γ球蛋白浓度相关。就疾病的临床活动而言，红细胞沉降率和血红蛋白似乎比Clq-BA和AC试验更好的参数。
