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10% 氯化锶牙膏治疗牙周手术后牙本质敏感的对照临床评估

Controlled clinical evaluation of a 10% strontium chloride dentifrice in treatment of dentin hypersensitivity following periodontal surgery.

作者信息

Uchida A, Wakano Y, Fukuyama O, Miki T, Iwayama Y, Okada H

出版信息

J Periodontol. 1980 Oct;51(10):578-81. doi: 10.1902/jop.1980.51.10.578.

DOI:10.1902/jop.1980.51.10.578
PMID:7003091
Abstract

Sixty adult patients were examined for dentin hypersensitivity prior to periodontal surgery. Stimuli used included mechanical, cold water and compressed air blasts. A subjective assessment of the degree of hypersensitivity for each stimulus was recorded. This presurgical examination revealed 249 hypersensitive areas among 60 subjects. Following surgery there was over a 100% increase in the pain (hypersensitivity) score. Desensitization with a 10% strontium chloride hexahydrate dentifrice was begun 1 week after surgical treatment. After 7 weeks of dentifrice use the pain score was reduced 75.5% in the test group. This was a reduction to a point below the preoperative level. The placebo group showed a reduction of 34.2% which was still above the preoperative level. These results agree with other clinical studies that have demonstrated a desensitizing effect of strontium chloride.

摘要

在进行牙周手术前,对60名成年患者进行了牙本质过敏检查。使用的刺激包括机械刺激、冷水和压缩空气喷射。记录了对每种刺激的过敏程度的主观评估。这项术前检查在60名受试者中发现了249个过敏区域。手术后,疼痛(过敏)评分增加了100%以上。手术治疗1周后开始使用含10%六水合氯化锶的牙膏进行脱敏治疗。在使用牙膏7周后,试验组的疼痛评分降低了75.5%。这一降低幅度使其降至术前水平以下。安慰剂组的疼痛评分降低了34.2%,仍高于术前水平。这些结果与其他证明氯化锶具有脱敏作用的临床研究一致。

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