关于克氏锥虫的染色质结构
On the chromatin structure of Trypanosoma cruzi.
作者信息
Astolfi Filho S, Martins de Sá C, Gander E S
出版信息
Mol Biochem Parasitol. 1980 Mar;1(1):45-53. doi: 10.1016/0166-6851(80)90040-7.
The chromatin structure of Trypanosoma cruzi was investigated. It was found that, as in other eukaryotes, the chromatin is organized in repeating units, the nucleosomes containing about 200 base pairs of DNA associated with histones. While there is no difference in the DNA size in nucleosomes from T. cruzi and from rat liver nuclei, the histone population of T. cruzi differs in various aspects. Of particular interest is the presence of two basic proteins, possibly histone H1 subcomponents, with very high electrophoretic mobilities.
对克氏锥虫的染色质结构进行了研究。发现与其他真核生物一样，染色质以重复单元的形式组织，核小体包含约200个与组蛋白相关的DNA碱基对。虽然克氏锥虫核小体中的DNA大小与大鼠肝细胞核中的DNA大小没有差异，但克氏锥虫的组蛋白群体在多个方面有所不同。特别令人感兴趣的是存在两种碱性蛋白，可能是组蛋白H1亚组分，具有非常高的电泳迁移率。
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