Lewis M, Bush G H
Anaesthesia. 1980 Oct;35(10):979-83. doi: 10.1111/j.1365-2044.1980.tb04996.x.
Twenty-four patients with pertussis admitted to a paediatric Intensive Care Unit over a period of 42 months are reviewed. It is concluded that pertussis affects the young baby most severely, the majority of the children admitted were under the age of 3 months. Many required long term intubation and pulmonary supportive therapy and the percentage of those admitted to the Intensive Care Unit who have needed mechanical ventilation has steadily increased over the period reviewed from 25 to 71%. The youngest infant died from overwhelming respiratory infection. The other 23 patients recovered but three children developed neurological complications and their recovery is still being assessed. The importance of maintenance of the immunisation programme is stressed in view of the evidence of the severity of the disease in the very young infant.
对42个月内收治于儿科重症监护病房的24例百日咳患儿进行了回顾性研究。得出的结论是,百日咳对小婴儿影响最为严重,大多数入院患儿年龄在3个月以下。许多患儿需要长期插管和肺部支持治疗,在回顾期间,入住重症监护病房且需要机械通气的患儿比例从25%稳步上升至71%。最年幼的婴儿死于严重的呼吸道感染。其他23例患儿康复,但有3名儿童出现了神经系统并发症,其恢复情况仍在评估中。鉴于有证据表明该疾病在小婴儿中病情严重,强调了维持免疫规划的重要性。