Schneider H M, Störkel S, Will W
Dtsch Med Wochenschr. 1980 Aug 15;105(33):1143-7. doi: 10.1055/s-2008-1070828.
After grading into 4 groups of severity the extent of amyloidosis of the islets of Langerhans was investigated in 60 patients with diabetes and in 60 without. Distinction of 3 stages of diabetes according to clinical parameters showed clear connections between the stage of diabetes and the extent of amyloidosis. Development of amyloid locally may be evidence for progressive B cell insufficiency in diabetes of adults.
在将60例糖尿病患者和60例非糖尿病患者的胰岛淀粉样变性程度分为4组严重程度后进行了研究。根据临床参数区分糖尿病的3个阶段显示,糖尿病阶段与淀粉样变性程度之间存在明显联系。局部淀粉样变的发生可能是成人糖尿病中进行性B细胞功能不全的证据。