通过预防性给予氨基糖苷类药物预防上行性肾盂肾炎
[Protection against ascending pyelonephritis by means of preventive aminoglucoside administration].
作者信息
Bille J, Glauser M P
出版信息
Schweiz Med Wochenschr. 1980 Dec 6;110(49):1886-7.
PMID:7006079
Abstract
Accumulated and persistent gentamicin in the kidney, when given prophylactically, affords protection against ascending obstructive E. coli pyelonephritis. Similar protection was observed after administration of tobramycin, netilmicine and amikacin, aminoglucoside antibiotics that accumulate to varying degrees in the renal parenchyma.
摘要
预防性给予庆大霉素后，其在肾脏中的蓄积和持续存在可预防上行性梗阻性大肠杆菌肾盂肾炎。在给予妥布霉素、奈替米星和阿米卡星后也观察到了类似的保护作用，这些氨基糖苷类抗生素在肾实质中会不同程度地蓄积。
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