Haynes R B, Taylor D W, Sackett D L, Gibson E S, Bernholz C D, Mukherjee J
Hypertension. 1980 Nov-Dec;2(6):757-64. doi: 10.1161/01.hyp.2.6.757.
Measurement of patient compliance is essential if management of low compliance is to be performed efficiently. We assessed the value of several easily obtained clinical assessments compared to quantitative pill counts among 134 newly treated hypertensive male steelworkers during the first 6 months of their treatment with antihypertensive medication. Patient's self-reports obtained on structured interview correlated best with pill count compliance (r = 0.74, p less than 0.0001). Patients overestimated their compliance by an average of 17% but 90% of those who admitted to being noncompliant were found so. Qualitative urinary chlorthalidone and hydrochlorothiazide levels and changes in serum potassium, uric acid, and blood pressure also correlated with pill count compliance but were less accurate than interviews. Assessment of the patient's "health beliefs" and a variety of sociodemographic and health traits and perceptions did not provide useful information on compliance. Interviewing the patient is a simple and useful approach in assessing compliance with antihypertensive therapy.
如果要有效地管理依从性差的情况，测量患者的依从性至关重要。我们评估了134名新接受治疗的男性高血压钢铁工人在接受抗高血压药物治疗的前6个月期间，几种易于获得的临床评估方法与定量药丸计数相比的价值。通过结构化访谈获得的患者自我报告与药丸计数依从性的相关性最佳（r = 0.74，p小于0.0001）。患者平均高估其依从性17%，但承认不依从的患者中有90%被发现确实不依从。定性尿氯噻酮和氢氯噻嗪水平以及血清钾、尿酸和血压的变化也与药丸计数依从性相关，但不如访谈准确。对患者“健康信念”以及各种社会人口统计学和健康特征及认知的评估并未提供关于依从性的有用信息。询问患者是评估抗高血压治疗依从性的一种简单而有用的方法。
