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聚异戊二烯对羟基苯甲酸羧化酶在鼠伤寒沙门氏菌鞭毛形成中的作用

Polyprenyl p-hydroxybenzoate carboxylase in flagellation of Salmonella typhimurium.

作者信息

Howlett B J, Bar-Tana J

出版信息

J Bacteriol. 1980 Aug;143(2):644-51. doi: 10.1128/jb.143.2.644-651.1980.

Abstract

Flagellation of Salmonella typhimurium was found to require a functional pathway for ubiquinone biosynthesis as well as growth in the presence of appropriate carboxylic acids. Induction of flagellation by carboxylic acids was shown to induce incorporation of p-hydroxybenzoic acid into polyprenylphenol. Constitutive flagellation was found to correlate with constitutive incorporation of p-hydroxybenzoic acid into polyprenylphenol. A novel pathway for polyprenyl p-hydroxybenzoic acid decarboxylation to polyprenylphenol was implicated in flagellation of S. typhimurium.

摘要

已发现鼠伤寒沙门氏菌的鞭毛形成需要泛醌生物合成的功能途径以及在适当羧酸存在下的生长。羧酸对鞭毛形成的诱导作用表现为对羟基苯甲酸掺入聚异戊二烯基酚中。组成型鞭毛形成与对羟基苯甲酸组成型掺入聚异戊二烯基酚中相关。一种新的聚异戊二烯基对羟基苯甲酸脱羧生成聚异戊二烯基酚的途径与鼠伤寒沙门氏菌的鞭毛形成有关。

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