Stock M J, Norgan N G, Ferro-Luzzi A, Evans E
J Appl Physiol Respir Environ Exerc Physiol. 1978 Sep;45(3):345-9. doi: 10.1152/jappl.1978.45.3.345.
Measurements of metabolic rate and the thermic response (specific dynamic action) of a 400-kcal liquid meal were made in six subjects at rest and during light exercise. The tests were conducted before (LA1) and after (LA2) a 3-wk sojourn (HA1, HA2, HA3) at 3,650 m on the Monte Rosa. Fasting metabolic rate at rest increased inittally and then fell, as did fasting and fed exercising metabolic rates. The fall in metabolic rates, but not the initial increases, can be ascribed to the change in body weight. Resting thermic responses at altitude were only slightly lower than normal, although peak values were significantly depressed at HA2 (P less than 0.05). The mean exercising thermic response was also significantly lower at HA2 (P less than 0.05) but recovered in HA3 and LA2. In the time taken for thermic responses to decrease and recover there were interindividual differences that were best explained by the previous altitude experience of the subjects. The possibility of a cardiovascular shift during hypoxic exercise causing depression of postprandial metabolism is discussed.
对六名受试者在静息状态和轻度运动期间的代谢率以及一顿400千卡流食的热效应（特殊动力作用）进行了测量。这些测试在他们于罗莎峰海拔3650米处进行为期3周的停留（HA1、HA2、HA3）之前（LA1）和之后（LA2）进行。静息时的空腹代谢率最初升高，然后下降，空腹和进食时的运动代谢率也是如此。代谢率的下降，而非最初的升高，可以归因于体重的变化。尽管在HA2时峰值显著降低（P小于0.05），但海拔高度下的静息热效应仅略低于正常水平。在HA2时，平均运动热效应也显著降低（P小于0.05），但在HA3和LA2时恢复。在热效应降低和恢复所需的时间上存在个体差异，这最好通过受试者之前的海拔经历来解释。文中讨论了低氧运动期间心血管变化导致餐后代谢降低的可能性。
