• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

巴尔通体:菌落类型与红细胞黏附

Bartonella bacilliformis: colonial types and erythrocyte adherence.

作者信息

Walker T S, Winkler H H

出版信息

Infect Immun. 1981 Jan;31(1):480-6. doi: 10.1128/iai.31.1.480-486.1981.

DOI:10.1128/iai.31.1.480-486.1981
PMID:7012005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC351807/
Abstract

Bartonella bacilliformis was cultivated on a solid medium, and two bartonella colonial morphologies were differentiated and designated colony types T1 and T2. Although both T1 and T2 bartonellae adhered to human erythrocytes in vitro, approximately twice as many T2 bartonellae adhered as did T1. Maximum adherence required bartonella energy, most likely proton motive force-dependent motility. Bartonellae did not penetrate or lyse erythrocytes in vitro. Bartonellae adhered poorly to alpha- or beta-glucosidase-treated erythrocytes, but pronase or subtilisin treatment of erythrocytes stimulated adherence. This indicates that bartonellae probably adhere to an erythrocyte glycolipid moiety.

摘要

杆菌状巴尔通体在固体培养基上培养,区分出两种巴尔通体菌落形态,并命名为T1和T2菌落类型。虽然T1和T2巴尔通体在体外均能黏附于人红细胞,但T2巴尔通体的黏附数量约为T1的两倍。最大黏附需要巴尔通体能量,很可能是质子动力依赖的运动性。巴尔通体在体外不会穿透或裂解红细胞。巴尔通体对α-或β-葡萄糖苷酶处理的红细胞黏附性差,但胰蛋白酶或枯草杆菌蛋白酶处理红细胞可刺激黏附。这表明巴尔通体可能黏附于红细胞糖脂部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d941/351807/b15111d3e00c/iai00165-0504-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d941/351807/9beb2bfc09d4/iai00165-0502-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d941/351807/78a6a174df9a/iai00165-0502-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d941/351807/b15111d3e00c/iai00165-0504-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d941/351807/9beb2bfc09d4/iai00165-0502-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d941/351807/78a6a174df9a/iai00165-0502-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d941/351807/b15111d3e00c/iai00165-0504-a.jpg

相似文献

1
Bartonella bacilliformis: colonial types and erythrocyte adherence.巴尔通体:菌落类型与红细胞黏附
Infect Immun. 1981 Jan;31(1):480-6. doi: 10.1128/iai.31.1.480-486.1981.
2
Entry of Bartonella bacilliformis into erythrocytes.杆菌状巴尔通体进入红细胞的过程。
Infect Immun. 1986 Nov;54(2):347-53. doi: 10.1128/iai.54.2.347-353.1986.
3
Interaction of Bartonella bacilliformis with human erythrocyte membrane proteins.巴尔通体杆菌与人类红细胞膜蛋白的相互作用。
Microb Pathog. 2000 Sep;29(3):165-74. doi: 10.1006/mpat.2000.0381.
4
Contact-dependent hemolytic activity distinct from deforming activity of Bartonella bacilliformis.与五日热巴尔通体变形活性不同的接触依赖性溶血活性。
FEMS Microbiol Lett. 2000 Jan 1;182(1):119-24. doi: 10.1111/j.1574-6968.2000.tb08884.x.
5
Establishing a direct role for the Bartonella bacilliformis invasion-associated locus B (IalB) protein in human erythrocyte parasitism.确定巴尔通体杆菌侵袭相关基因座B(IalB)蛋白在人类红细胞寄生中的直接作用。
Infect Immun. 2001 Jul;69(7):4373-81. doi: 10.1128/IAI.69.7.4373-4381.2001.
6
Characterization of Bartonella bacilliformis flagella and effect of antiflagellin antibodies on invasion of human erythrocytes.杆菌状巴尔通体鞭毛的特性及抗鞭毛蛋白抗体对人红细胞入侵的影响
Infect Immun. 1993 Dec;61(12):4962-71. doi: 10.1128/iai.61.12.4962-4971.1993.
7
Invasion and persistent intracellular colonization of erythrocytes. A unique parasitic strategy of the emerging pathogen Bartonella.红细胞的入侵和持续细胞内定植。新兴病原体巴尔通体独特的寄生策略。
J Exp Med. 2001 May 7;193(9):1077-86. doi: 10.1084/jem.193.9.1077.
8
Adhesion to and invasion of cultured human cells by Bartonella bacilliformis.杆状巴尔通体对培养的人细胞的黏附和侵袭
Infect Immun. 1992 Oct;60(10):4051-8. doi: 10.1128/iai.60.10.4051-4058.1992.
9
Bartonella entry mechanisms into mammalian host cells.巴尔通体进入哺乳动物宿主细胞的机制。
Cell Microbiol. 2012 Aug;14(8):1166-73. doi: 10.1111/j.1462-5822.2012.01806.x. Epub 2012 May 16.
10
Bartonella bacilliformis: dangerous pathogen slowly emerging from deep background.巴尔通体:一种正从隐匿背景中缓慢浮现的危险病原体。
FEMS Microbiol Lett. 1996 Oct 15;144(1):1-11. doi: 10.1111/j.1574-6968.1996.tb08501.x.

引用本文的文献

1
and Its Hidden Flagellar System.及其隐藏的鞭毛系统。
Microorganisms. 2021 Dec 31;10(1):83. doi: 10.3390/microorganisms10010083.
2
Carrion's disease: more than a neglected disease.卡利翁氏病:不仅仅是一种被忽视的疾病。
Parasit Vectors. 2019 Mar 26;12(1):141. doi: 10.1186/s13071-019-3390-2.
3
Molecular Mechanisms of and Mammalian Erythrocyte Interactions: A Review.与哺乳动物红细胞相互作用的分子机制:综述。

本文引用的文献

1
[New investigations on Bartonella bacilliformis. I. Morphology of cultured variety].[杆菌状巴尔通体的新研究。I. 培养变种的形态学]
Z Tropenmed Parasitol. 1952 Feb;3(3):313-26.
2
NEISSERIA GONORRHOEAE. I. VIRULENCE GENETICALLY LINKED TO CLONAL VARIATION.淋病奈瑟菌。一、与克隆变异基因连锁的毒力。
J Bacteriol. 1963 Jun;85(6):1274-9. doi: 10.1128/jb.85.6.1274-1279.1963.
3
The hemolytic anemia of human bartonellosis.人类巴尔通体病的溶血性贫血
Front Cell Infect Microbiol. 2018 Dec 12;8:431. doi: 10.3389/fcimb.2018.00431. eCollection 2018.
4
Carrion's Disease: the Sound of Silence.卡利翁病:无声的喧嚣。
Clin Microbiol Rev. 2017 Nov 29;31(1). doi: 10.1128/CMR.00056-17. Print 2018 Jan.
5
Development and characterisation of highly antibiotic resistant Bartonella bacilliformis mutants.高度耐抗生素的杆状巴尔通体突变体的开发与特性分析
Sci Rep. 2016 Sep 26;6:33584. doi: 10.1038/srep33584.
6
Oroya fever and verruga peruana: bartonelloses unique to South America.奥罗亚热和秘鲁疣:南美洲特有的巴尔通体病。
PLoS Negl Trop Dis. 2014 Jul 17;8(7):e2919. doi: 10.1371/journal.pntd.0002919. eCollection 2014 Jul.
7
Bartonella and Brucella--weapons and strategies for stealth attack.巴尔通体和布鲁氏菌——用于秘密攻击的武器和策略。
Cold Spring Harb Perspect Med. 2013 Aug 1;3(8):a010231. doi: 10.1101/cshperspect.a010231.
8
Novel Bartonella agent as cause of verruga peruana.新型巴尔通体病原体引起秘鲁疣。
Emerg Infect Dis. 2013 Jul;19(7):1111-4. doi: 10.3201/eid1907.121718.
9
Identification of Bartonella Trw host-specific receptor on erythrocytes.鉴定红细胞上的巴尔通体 trw 种属特异性受体。
PLoS One. 2012;7(7):e41447. doi: 10.1371/journal.pone.0041447. Epub 2012 Jul 26.
10
Intruders below the radar: molecular pathogenesis of Bartonella spp.雷达之下的入侵者:巴尔通体属的分子发病机制
Clin Microbiol Rev. 2012 Jan;25(1):42-78. doi: 10.1128/CMR.05009-11.
Blood. 1961 May;17:562-78.
4
Study on growth of Rickettsia. V. Penetration of Rickettsia tsutsugamushi into mammalian cells in vitro.立克次氏体生长的研究。V. 恙虫病立克次氏体在体外对哺乳动物细胞的穿透。
J Exp Med. 1959 Mar 1;109(3):271-92. doi: 10.1084/jem.109.3.271.
5
[New studies on Bartonelle bacilliformis. 4. Electron-optical study of blood smears containing Bartonella bacilliformis].[巴尔通体杆菌的新研究。4. 含巴尔通体杆菌血涂片的电子光学研究]
Z Tropenmed Parasitol. 1953 Oct;4(4):539-48.
6
[Further research on Bartonella bacilliformis. III. Experiments with Rhesus monkeys and body lice on transmissibility of the disease].[巴尔通体杆菌的进一步研究。III. 恒河猴和体虱对该疾病传播性的实验]
Z Tropenmed Parasitol. 1953 Mar;4(2):243-54.
7
The relationship of Bartonella bacilliformis to the red blood cell as revealed by electron microscopy.
Blood. 1969 May;33(5):708-16.
8
A history of bartonellosis (Carrión's disease).
Am J Trop Med Hyg. 1968 Jul;17(4):503-15. doi: 10.4269/ajtmh.1968.17.503.
9
Rickettsial hemolysis: effect of metabolic inhibitors upon hemolysis and adsorption.立克次氏体溶血:代谢抑制剂对溶血和吸附的影响
Infect Immun. 1973 Apr;7(4):550-5. doi: 10.1128/iai.7.4.550-555.1973.
10
Role of pili in the virulence of Neisseria gonorrhoeae.菌毛在淋病奈瑟菌毒力中的作用。
Infect Immun. 1973 Aug;8(2):255-63. doi: 10.1128/iai.8.2.255-263.1973.