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来自大肠杆菌的化学引诱因子:菌株个体差异

Chemoattractive factors from Escherichia coli: individual strain variation.

作者信息

Belsheim J, Gnarpe H, Kaijser B

出版信息

Infect Immun. 1981 Jan;31(1):7-10. doi: 10.1128/iai.31.1.7-10.1981.

Abstract

Thirty-five different Escherichia coli strains isolated from patients with asymptomatic bacteriuria, cystitis, or pyelonephritis were investigated regarding their capacity to stimulate leukocyte chemotaxis in vitro. There were significant differences between individual strains in degree of chemoattraction, as well as among individual leukocyte donors in their reactions to the same strains. These differences were not correlated to specific E. coli antibodies. No significant differences in chemoattraction were found among strains isolated from patients with asymptomatic bacteriuria, cystitis, or pyelonephritis. It was suggested that the production of chemoattractive factors was not important for the pathogenicity of different E. coli strains in relation to urinary tract infection.

摘要

对从无症状菌尿症、膀胱炎或肾盂肾炎患者中分离出的35种不同大肠杆菌菌株进行了体外刺激白细胞趋化性能力的研究。各菌株在趋化吸引程度上存在显著差异,并且不同白细胞供体对同一菌株的反应也存在差异。这些差异与特异性大肠杆菌抗体无关。从无症状菌尿症、膀胱炎或肾盂肾炎患者中分离出的菌株在趋化吸引方面未发现显著差异。研究表明,趋化吸引因子的产生对于不同大肠杆菌菌株在尿路感染中的致病性并不重要。

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Abnormalities of leukocyte chemotaxis in human disease.人类疾病中白细胞趋化性异常。
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Level diagnosis of symptomatic urinary tract infections in childhood.
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