Iosefsohn M, Hicks J M
Ther Drug Monit. 1980;2(3):249-53. doi: 10.1097/00007691-198007000-00008.
We compared results of theophylline, phenobarbital, and phenytoin assays by the EMIT method using the IL Multistat III Micro Centrifugal Analyzer with results by the EMIT semiautomated procedure on a Beckman 25 spectrophotometer equipped with a semiautomated pipettor-dilutor and a model 2400 automatic timer/printer. We assessed linearity, precision, specificity, and correlation with other methods, The IL MCA III is precise, easy to use, and suitable for routine use in a pediatric laboratory. Only 3 microliter of serum is used for each drug analysis, and 17 results can be obtained in 8 min. Reagent costs can be reduced fourfold.
我们使用IL Multistat III微量离心机分析仪，通过EMIT方法比较了茶碱、苯巴比妥和苯妥英的检测结果，并将其与在配备半自动移液器-稀释器和2400型自动定时器/打印机的贝克曼25分光光度计上采用EMIT半自动程序得出的结果进行了比较。我们评估了线性、精密度、特异性以及与其他方法的相关性。IL MCA III精密度高、易于使用，适用于儿科实验室的常规检测。每次药物分析仅需3微升血清，8分钟内可获得17个结果。试剂成本可降低四倍。
