• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

大鼠腹膜和肺泡巨噬细胞群体的异质性：用抗血清对其表面抗原进行表征。

Heterogeneity of rat peritoneal and alveolar macrophage populations: characterization of their surface antigens by antisera.

作者信息

Thomas M A, Macsween R N

出版信息

Br J Exp Pathol. 1981 Feb;62(1):65-73.

PMID:7013777
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2041636/
Abstract

Antisera were raised in rabbits against rat peritoneal and alveolar macrophages and against rat thymocytes. In vitro investigations of these antisera using dye-exclusion tests and cytotoxicity and immunofluorescence methods indicated that the immunizing cell types exhibited shared and specific antigens. Extensive absorption studies confirmed these findings, and showed some specificity of the anti-peritoneal serum for peritoneal macrophages and of the anti-alveolar serum for alveolar cells.

摘要

用大鼠腹膜巨噬细胞、肺泡巨噬细胞和胸腺细胞免疫家兔制备抗血清。运用染料排除试验、细胞毒性试验和免疫荧光法对这些抗血清进行的体外研究表明，免疫细胞类型呈现出共同抗原和特异性抗原。广泛的吸收研究证实了这些发现，并显示抗腹膜血清对腹膜巨噬细胞具有一定特异性，抗肺泡血清对肺泡细胞具有一定特异性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de7/2041636/a88367e16e59/brjexppathol00109-0083-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de7/2041636/a88367e16e59/brjexppathol00109-0083-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1de7/2041636/a88367e16e59/brjexppathol00109-0083-a.jpg

相似文献

1
Heterogeneity of rat peritoneal and alveolar macrophage populations: characterization of their surface antigens by antisera.大鼠腹膜和肺泡巨噬细胞群体的异质性：用抗血清对其表面抗原进行表征。
Br J Exp Pathol. 1981 Feb;62(1):65-73.
2
Antigenic differences between alveolar and peritoneal macrophages of the rat. Lack of population-specific determinants.大鼠肺泡巨噬细胞与腹腔巨噬细胞之间的抗原差异。缺乏群体特异性决定簇。
Immunology. 1979 Nov;38(3):621-30.
3
Demonstration of two distinct macrophage specific antigenic determinants in rats.大鼠体内两种不同巨噬细胞特异性抗原决定簇的证实。
Adv Exp Med Biol. 1976;66:153-8. doi: 10.1007/978-1-4613-4355-4_23.
4
Natural and induced antisera specific for pulmonary macrophages.针对肺巨噬细胞的天然和诱导抗血清。
Lung. 1984;162(3):171-82. doi: 10.1007/BF02715645.
5
Differences in the cytotoxic effect of rabbit anti-rat macrophage sera on rat alveolar and peritoneal macrophages.兔抗大鼠巨噬细胞血清对大鼠肺泡巨噬细胞和腹腔巨噬细胞细胞毒性作用的差异。
Immunobiology. 1980 Jan;156(4-5):331-41. doi: 10.1016/S0171-2985(80)80067-2.
6
Peritoneal exudate T lymphocytes with specificity to sheep red blood cells. III. High dose of antigen induces suppressor T cells which influence the appearance in exudates of effector T cells for delayed-type hypersensitivity and helper T cells for humoral immune responses.对绵羊红细胞具有特异性的腹腔渗出液T淋巴细胞。III. 高剂量抗原诱导抑制性T细胞，这些抑制性T细胞会影响迟发型超敏反应效应T细胞和体液免疫反应辅助性T细胞在渗出液中的出现。
Immunology. 1979 Nov;38(3):613-9.
7
Alveolar macrophages. V. Comparative studies on the antigen presentation activity of guinea-pig and rat alveolar macrophages.肺泡巨噬细胞。V.豚鼠和大鼠肺泡巨噬细胞抗原呈递活性的比较研究。
Immunology. 1980 Oct;41(2):361-6.
8
Antigenic differences between rat alveolar and peritoneal macrophages.大鼠肺泡巨噬细胞与腹腔巨噬细胞之间的抗原差异。
Adv Exp Med Biol. 1976;73 PT-A:53-8. doi: 10.1007/978-1-4684-3297-8_5.
9
Surface antigens of murine hemopoietic stem cells. VIII. Antisera define lineage antigens held in common between granulocyte-macrophage cells and between lymphoid cells.小鼠造血干细胞的表面抗原。VIII. 抗血清确定粒细胞-巨噬细胞之间以及淋巴细胞之间共有的谱系抗原。
Int J Cell Cloning. 1983 Oct;1(5):360-76. doi: 10.1002/stem.5530010504.
10
IgE immune complexes induce immediate and prolonged release of leukotriene C4 (LTC4) from rat alveolar macrophages.IgE免疫复合物可诱导大鼠肺泡巨噬细胞立即并持续释放白三烯C4（LTC4）。
J Immunol. 1984 Apr;132(4):1993-9.

引用本文的文献

1
Intraperitoneal infection with scrapie is established within minutes of injection and is non-specifically enhanced by a variety of different drugs.腹腔注射瘙痒病病原体后几分钟内即可引发腹腔感染，并且多种不同药物可非特异性增强这种感染。
Arch Virol. 1990;112(1-2):103-14. doi: 10.1007/BF01348988.

本文引用的文献

1
THE ORIGIN OF MACROPHAGES FROM BONE MARROW IN THE RAT.大鼠骨髓中巨噬细胞的起源
Br J Exp Pathol. 1965 Feb;46(1):62-70.
2
EFFECTS OF SIMPLE LIPIDS ON THE PHAGOCYTIC PROPERTIES OF PERITONEAL MACROPHAGES. II. STUDIES ON THE PHAGOCYTIC POTENTIAL OF CELL POPULATIONS.简单脂质对腹膜巨噬细胞吞噬特性的影响。II. 细胞群体吞噬潜力的研究。
Aust J Exp Biol Med Sci. 1964 Jun;42:429-42. doi: 10.1038/icb.1964.40.
3
ENZYMATIC DIFFERENCES BETWEEN NORMAL ALVEOLAR MACROPHAGES AND OIL-INDUCED PERITONEAL MACROPHAGES OBTAINED FROM RABBITS.从兔子获得的正常肺泡巨噬细胞与油诱导的腹膜巨噬细胞之间的酶学差异。
Exp Cell Res. 1964 Feb;33:553-61. doi: 10.1016/0014-4827(64)90020-5.
4
THE PARTICULATE HYDROLASES OF MACROPHAGES. I. COMPARATIVE ENZYMOLOGY, ISOLATION, AND PROPERTIES.巨噬细胞的颗粒水解酶。I. 比较酶学、分离及特性
J Exp Med. 1963 Dec 1;118(6):991-1008. doi: 10.1084/jem.118.6.991.
5
Studies on pulmonary alveolar macrophages from the normal rabbit: a technique to procure them in a high state of purity.对正常兔肺泡巨噬细胞的研究：一种获取高纯度肺泡巨噬细胞的技术。
J Immunol. 1961 Feb;86:128-32.
6
Chemotoxis of mononuclear cells.单核细胞的化学毒性
J Exp Med. 1968 Nov 1;128(5):1201-21. doi: 10.1084/jem.128.5.1201.
7
Studies on antimacrophage globulin.抗巨噬细胞球蛋白的研究。
Clin Exp Immunol. 1971 May;8(5):801-14.
8
Antigenic structure of cell surfaces. An immunoferritin study of the occurrence and topography of H-2' theta, and TL alloantigens on mouse cells.细胞表面的抗原结构。关于小鼠细胞上H-2'θ和TL同种异体抗原的出现及定位的免疫铁蛋白研究。
J Exp Med. 1969 Nov 1;130(5):979-1001. doi: 10.1084/jem.130.5.979.
9
Origin and kinetics of monocytes and macrophages.单核细胞和巨噬细胞的起源与动力学
Semin Hematol. 1970 Apr;7(2):125-41.
10
The functional heterogeneity of macrophages at the single cell level.巨噬细胞在单细胞水平上的功能异质性。
Aust J Exp Biol Med Sci. 1967 Dec;45(6):675-80. doi: 10.1038/icb.1967.67.