Sheikh T K, Charron R C, Katz A
Am J Clin Pathol. 1981 May;75(5):755-62. doi: 10.1093/ajcp/75.5.755.
Renal failure secondary to crescentic glomerulonephritis developed in a patient who had typical serologic features of drug-induced systemic lupus erythematosus after two years of therapy with procainamide. Renal function and proteinuria improved after the drug was discontinued and steroid therapy begun. A review of previously reported cases of glomerulonephritis in association with drug-induced systemic lupus erythematosus revealed a high incidence of renal failure. Crescentic glomerulonephritis has not to our knowledge been previously documented in drug-induced systemic lupus erythematosus.
一名患者在接受普鲁卡因胺治疗两年后出现了继发于新月体性肾小球肾炎的肾衰竭,该患者具有药物性系统性红斑狼疮的典型血清学特征。停药并开始使用类固醇治疗后,肾功能和蛋白尿有所改善。对先前报道的与药物性系统性红斑狼疮相关的肾小球肾炎病例进行回顾发现,肾衰竭的发生率很高。据我们所知,新月体性肾小球肾炎此前尚未在药物性系统性红斑狼疮中被记录过。