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[同种异体肾移植包膜下压力的测量:一种术后移植监测的新方法]

[Measurement of the subcapsular pressure of allogeneic kidney transplants: a new method for postoperative transplant monitoring].

作者信息

Wagner E, Tidow G, Pichlmayr R

出版信息

Klin Wochenschr. 1981 Apr 1;59(7):311-4. doi: 10.1007/BF01524999.

Abstract

The results presented here show the measurement of the subcapsular hydrostatic pressure (SHP) to be a suitable method for the postoperative monitoring of a allogeneic kidney transplants. The SHP of the kidney reflects the interstitial pressure of this organ. Disturbances in the graft of immunological or non-immunological origin induce pressure increases with, for the most part, specific characteristics. An examination of the height and course of the mean subcapsular pressure level enables one to recognise and differentiate disturbances in transplant function at an early stage as well as assess their severity and duration. The results obtained so far show that the measurement of the subcapsular pressure is of particular significance in determining the extent of ischemic tubular damage, in early recognition of acute rejection and i assessing the effectiveness of immunosuppresive treatment for rejection. Repeated pressure measurements with the method described here can be performed with little technical outlay and without any stress for the patient.

摘要

此处呈现的结果表明,测量肾包膜下静水压(SHP)是术后监测同种异体肾移植的一种合适方法。肾脏的SHP反映了该器官的间质压力。免疫或非免疫源性移植物的干扰会导致压力升高,且在很大程度上具有特定特征。检查平均肾包膜下压力水平的高度和变化过程,能够使人在早期识别和区分移植功能的干扰,并评估其严重程度和持续时间。目前获得的结果表明,测量肾包膜下压力在确定缺血性肾小管损伤的程度、早期识别急性排斥反应以及评估免疫抑制治疗对排斥反应的有效性方面具有特别重要的意义。使用此处所述方法进行重复压力测量,技术成本低,且不会给患者带来任何压力。

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