Barst R J, Prince A S, Neu H C
Pediatrics. 1981 Jul;68(1):73-8.
Aspergillus fumigatus endocarditis developed in a 2 1/2-year-old girl after repair of tetralogy of Fallot. There have been 14 other cases of Aspergillus endocarditis in children described in the literature. Fever and embolic phenomenon, particularly to the CNS, were the most common presenting manifestations. Consumptive coagulopathy developed in this patient as it has in other children and should suggest the diagnosis of Aspergillus endocarditis inasmuch as blood cultures are uniformly negative. Antemortem diagnosis was made in four of 15 patients. Only one patient survived the infection. Environmental surveillance is crucial when a case is encountered. Survival of the infected patient occurs only with early diagnosis and surgical removal of the infected tissue.
一名2岁半的女孩在法洛四联症修复术后发生了烟曲霉心内膜炎。文献中还描述了另外14例儿童曲霉性心内膜炎病例。发热和栓塞现象，尤其是中枢神经系统栓塞，是最常见的临床表现。该患者出现了消耗性凝血病，其他儿童也有这种情况，鉴于血培养均为阴性，应考虑曲霉性心内膜炎的诊断。15例患者中有4例在生前做出了诊断。只有1例患者在感染后存活。遇到此类病例时，环境监测至关重要。只有早期诊断并手术切除感染组织，感染患者才能存活。
