Schwartz D A
Trop Geogr Med. 1981 Mar;33(1):1-7.
This article reviews the association between bilharziasis and bladder cancer. Cancer of the bladder is a well documented sequelae of chronic infection with Schistosoma haematobium. Bilharzial bladder cancer is a major cause of morbidity in many countries; it remains the most commonly diagnosed cancer of Egyptian men. Bilharzial tumors may be differentiated from non-bilharzial tumors by their younger age of onset, greater male/female ratio, pathology and clinical presentation. Bladder tumors have been successfully induced in animals exposed to S. haematobium cercariae. Dietary nitrosamines may exacerbate the induction of bladder cancer in the presence of S. haematobium. The exact mechanism of bilharzial bladder carcinogenesis remains unknown.
本文综述了血吸虫病与膀胱癌之间的关联。膀胱癌是埃及血吸虫慢性感染的一种有充分文献记载的后遗症。血吸虫性膀胱癌是许多国家发病的主要原因；它仍然是埃及男性最常被诊断出的癌症。血吸虫性肿瘤可因其发病年龄较轻、男女比例较高、病理和临床表现与非血吸虫性肿瘤相鉴别。在接触埃及血吸虫尾蚴的动物中已成功诱发膀胱肿瘤。在存在埃及血吸虫的情况下，膳食亚硝胺可能会加剧膀胱癌的诱发。血吸虫性膀胱癌的确切发病机制仍然未知。
