Eiermann W, Albrich W, Dati F, Leis D, Eicher W
Geburtshilfe Frauenheilkd. 1981 Jun;41(6):404-6. doi: 10.1055/s-2008-1037187.
The enzyme immunologic determination of SP1 in the serum is suitable for the early diagnosis of pregnancy from 14 days after ovulation onwards. In the control group of 64 non-pregnant and of healthy men no SP1 was detected in the serum. At least six weeks after the cessation of trophoblast activity SP1 can still be detected in the serum. The enzyme immunoassay technique of SP1 in the serum has a high sensitivity of 1 ng/SP1/ml serum and a short measuring time of 2 1/2-4 hours. This test is therefore excellent for the early diagnosis of pregnancy.