Thyroid function in chronic renal failure after successful renal transplantation.

Chronic renal failure is associated with a variety of thyroid function abnormalities. Information on thyroid function in patients with chronic renal failure after successful renal transplantation is limited. We studied thyroid function in 13 such patients and found that serum TT3 in the transplant group (136 +/- 30 ng/ml) was significantly (P less than 0.01) higher than the TT3 in the control group (112 +/- 29 ng/ml). All patients were clinically euthyroid and had normal serum TT4, FT4, FT3, TSH, and TBG levels and a normal T3 resin uptake. The pathogenesis of the observed increased TT3 in these patients is not clear.