Vaziri N D, Gwinup G, Martin D, Seltzer J
Clin Nephrol. 1981 Mar;15(3):131-4.
Chronic renal failure is associated with a variety of thyroid function abnormalities. Information on thyroid function in patients with chronic renal failure after successful renal transplantation is limited. We studied thyroid function in 13 such patients and found that serum TT3 in the transplant group (136 +/- 30 ng/ml) was significantly (P less than 0.01) higher than the TT3 in the control group (112 +/- 29 ng/ml). All patients were clinically euthyroid and had normal serum TT4, FT4, FT3, TSH, and TBG levels and a normal T3 resin uptake. The pathogenesis of the observed increased TT3 in these patients is not clear.
慢性肾衰竭与多种甲状腺功能异常有关。关于慢性肾衰竭患者成功肾移植后甲状腺功能的信息有限。我们研究了13例此类患者的甲状腺功能，发现移植组患者的血清总三碘甲状腺原氨酸（TT3）（136±30 ng/ml）显著高于对照组（112±29 ng/ml）（P<0.01）。所有患者临床甲状腺功能正常，血清总甲状腺素（TT4）、游离甲状腺素（FT4）、游离三碘甲状腺原氨酸（FT3）、促甲状腺激素（TSH）和甲状腺素结合球蛋白（TBG）水平正常，三碘甲状腺原氨酸摄取率正常。这些患者中观察到的TT3升高的发病机制尚不清楚。
