低剂量1%胍乙啶与0.5%肾上腺素联合治疗慢性单纯性青光眼：一项前瞻性研究。
Low-dose combined guanethedine 1% and adrenaline 0.5% in the treatment of chronic simple glaucoma: a prospective study.
作者信息
Murray A, Glover D, Hitchings R
出版信息
Br J Ophthalmol. 1981 Aug;65(8):533-5. doi: 10.1136/bjo.65.8.533.
Abstract
This paper reports on the results of a prospective double-blind crossover study, comparing adrenaline 1% with adrenaline 0.5% combined with guanethedine 1% over an 8-week period with each formulation. The guanethedine/adrenaline formulation was found to be the more effective hypotensive agent of the two. This study confirms the potentiating effect of adding guanethedine to adrenaline, and suggests that this combination would be a useful alternative treatment when adrenaline 1% or adrenaline 0.25% with guanethedine 1% is insufficient.
摘要
本文报告了一项前瞻性双盲交叉研究的结果，在为期8周的时间里，将1%肾上腺素与0.5%肾上腺素联合1%胍乙啶的两种配方进行比较。结果发现，胍乙啶/肾上腺素配方是两者中更有效的降压药。本研究证实了在肾上腺素中添加胍乙啶的增效作用，并表明当1%肾上腺素或0.25%肾上腺素与1%胍乙啶疗效不足时，这种联合用药将是一种有用的替代治疗方法。
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Low-dose combined guanethedine 1% and adrenaline 0.5% in the treatment of chronic simple glaucoma: a prospective study.低剂量1%胍乙啶与0.5%肾上腺素联合治疗慢性单纯性青光眼：一项前瞻性研究。
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引用本文的文献
1
Adrenaline 1% combined with guanethidine 1% versus adrenaline 1%: a randomised prospective double-blind cross-over study.
Br J Ophthalmol. 1982 Apr;66(4):247-9. doi: 10.1136/bjo.66.4.247.
本文引用的文献
1
Topical epinephrine therapy of open-angel glaucoma.开角型青光眼的局部肾上腺素治疗
Arch Ophthalmol. 1961 Aug;66:219-25. doi: 10.1001/archopht.1961.00960010221012.
2
Double-masked cross-over comparison of Ganda 1.02 (guanethidine 1% and adrenaline 0.2% mixture) with gutt. adrenaline 1% (Simplene 1%) and with pilocarpine 1% (Sno-Pilo 1%).将甘达1.02（胍乙啶1%与肾上腺素0.2%的混合物）与1%肾上腺素滴眼液（辛普伦1%）以及1%毛果芸香碱（斯诺-匹罗1%）进行双盲交叉比较。
Br J Ophthalmol. 1981 Jan;65(1):50-2. doi: 10.1136/bjo.65.1.50.
3
Guanethidine and adrenaline used in combination in chronic simple glaucoma.胍乙啶与肾上腺素联合用于慢性单纯性青光眼。
Br J Ophthalmol. 1973 Jul;57(7):507-10. doi: 10.1136/bjo.57.7.507.
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Guanethidine and glaucoma.胍乙啶与青光眼
Trans Ophthalmol Soc U K (1962). 1974 Jul;94(2):573-7.
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Low centration guanethidine and adrenaline therapy of glaucoma. A preliminary report.
Trans Ophthalmol Soc U K (1962). 1976 Apr;96(1):179-83.
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Use of guanethidine 5% and adrenaline 1% in the treatment of severe open angle glaucoma.
Trans Ophthalmol Soc U K (1962). 1977 Apr;97(1):196-201.
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Low dosage combined adrenaline-guanethidine formulations in the management of chronic simple glaucoma.
Trans Ophthalmol Soc U K (1962). 1977 Apr;97(1):192-5.
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