利福平或金霉素局部治疗衣原体眼部感染（沙眼衣原体感染）的双盲比较。
A double-blind comparison of topical therapy of chlamydial ocular infection (TRIC infection) with rifampicin or chlortetracycline.
作者信息
Darougar S, Viswalingam N, El-Sheikh H, Hunter P A, Yearsley P
出版信息
Br J Ophthalmol. 1981 Aug;65(8):549-52. doi: 10.1136/bjo.65.8.549.
Abstract
A double-blind stratified trial was carried out on 85 patients to assess the efficacy of topical therapy with 1% chlortetracycline eye ointment in comparison with 1% rifampicin eye ointment in the treatment of chlamydial ocular infection of sexually transmitted origin (paratrachoma). Patients included were selected on the basis of positive culture for Chlamydia trachomatis. A 6-week course of treatment with chlortetracycline or rifampicin 3 times daily gave a clinical cure rate of 80% and 75% and a microbiological cure rate of 93% and 86% respectively. In patients who were not cured the intensity of inflammatory responses was considerably reduced.
摘要
对85例患者进行了一项双盲分层试验，以评估1%金霉素眼膏局部治疗与1%利福平眼膏相比，在治疗性传播衣原体眼部感染（沙眼性炎症）中的疗效。纳入的患者基于沙眼衣原体培养阳性进行选择。金霉素或利福平每日3次，为期6周的治疗疗程，临床治愈率分别为80%和75%，微生物治愈率分别为93%和86%。在未治愈的患者中，炎症反应强度显著降低。
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本文引用的文献
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