Pène P, Vincentelli J M, Soula G, Delmont J, Rossignol J F
Bull Soc Pathol Exot Filiales. 1981 Nov-Dec;74(6):590-4.
A randomized double-blind study, in order to evaluate effectiveness and tolerance of albendazole, was carried out in 186 african subjects presenting intestinal nematode infections in Mali and Senegal. The drug, well tolerated, given as a single dose of 0.4 g (adolescents and adults) or 0.2 g (children) is curative in more than 90% for ascariasis. For ancylostomiasis and trichuriasis, the effectiveness is less satisfactory in children, probably due to insufficient dosage in this age group.
为评估阿苯达唑的有效性和耐受性，在马里和塞内加尔对186名患有肠道线虫感染的非洲受试者进行了一项随机双盲研究。该药物耐受性良好，单剂量给药，青少年和成人服用0.4克，儿童服用0.2克，对蛔虫病的治愈率超过90%。对于钩虫病和鞭虫病，该药物在儿童中的疗效不太理想，这可能是由于该年龄组的剂量不足所致。
