Sanderson A, Walliker D, Molez J F
Trans R Soc Trop Med Hyg. 1981;75(2):263-7. doi: 10.1016/0035-9203(81)90331-x.
Freeze-dried and freshly cultured isolates of Plasmodium falciparum from different countries have been examined for variation in six enzymes, GPI, PGD, LDH, GDH, ADA and PEPE, using starch gel electrophoresis. Variant forms of each enzyme occur. For most enzymes, similar forms occur in isolates from different parts of the world, although differences in frequencies of each form are found. LDH-2 has been found only in African isolates. PEPE variants vary markedly in their frequency between East and West Africa, although further work is needed to confirm this finding.
已使用淀粉凝胶电泳法，对来自不同国家的恶性疟原虫冻干和新鲜培养分离株的六种酶（糖基磷脂酰肌醇、6-磷酸葡萄糖脱氢酶、乳酸脱氢酶、谷氨酸脱氢酶、腺苷脱氨酶和肽酶）的变异情况进行了检测。每种酶都存在变异形式。对于大多数酶而言，尽管每种形式的频率存在差异，但在来自世界不同地区的分离株中都出现了相似的形式。仅在非洲分离株中发现了乳酸脱氢酶-2。虽然还需要进一步的研究来证实这一发现，但肽酶变体在东非和西非之间的频率差异显著。
