Aggleton J P, Passingham R E
Exp Brain Res. 1981;44(3):271-6. doi: 10.1007/BF00236564.
The anterior/posterior (AP) positions of three subcortical regions; the amygdala, supra-optic nucleus of the hypothalamus and mammillary bodies, were estimated with respect to the skull in 35 rhesus monkeys (Macaca mulatta). The distances from the external auditory meatus, from which stereotaxic coordinates are typically derived, to these subcortical nuclei were found to be highly variable. In contrast the posterior tip of the sphenoid bone, which was visualized on lateral radiographs, provided a landmark at a remarkably constant AP distance from these nuclei. This landmark was used to guide a series of a amygdaloid lesions and injections. The accuracy of these operations strongly suggested that the posterior tip of the sphenoid bone could be used to predict not only the AP but also the height of the amygdala. It is proposed that this radiographic technique could be applied to other hypothalamic and basal forebrain regions.
在35只恒河猴（猕猴）中，相对于颅骨估计了三个皮质下区域（杏仁核、下丘脑视上核和乳头体）的前后（AP）位置。发现从通常获取立体定向坐标的外耳道到这些皮质下核的距离变化很大。相比之下，在侧位X线片上可见的蝶骨后尖端，与这些核的AP距离相当恒定，可作为一个标志。这个标志被用来指导一系列杏仁核损伤和注射操作。这些操作的准确性有力地表明，蝶骨后尖端不仅可用于预测杏仁核的前后位置，还可用于预测其高度。建议将这种放射学技术应用于其他下丘脑和基底前脑区域。
