慢性肾功能衰竭及肾移植后α1抗胰蛋白酶和纤维蛋白原水平（作者译）
[Alpha-1-antitrypsin and fibrinogen levels in chronic renal failure and after kidney transplantation (author's transl)].
作者信息
Zazgornik J, Balcke P, Schmidt P, Kopsa H, Hysek H, Lenz K
出版信息
Klin Wochenschr. 1981 Nov 16;59(22):1261-5. doi: 10.1007/BF01747758.
In ten non dialyzed patients with chronic renal failure, 18 patients on regular dialysis treatment and 70 renal transplant recipients alpha-1-antitrypsin and fibrinogen levels were investigated. Alpha-1-antitrypsin and fibrinogen concentrations were highest in dialyzed patients with values of 314 +/- 98 and 485 +/- 127 mg/dl respectively. In renal transplant recipients a significant positive correlation between alpha-1-antitrypsin and fibrinogen concentration was found (p less than 0.001). High alpha-1-antitrypsin and fibrinogen levels seem to be a possible consequence of reactive processes due to underlying disease or complications. Our results seem to indicate that both alpha 1-antitrypsin and fibrinogen can be classified as "acute phase protein".
对10例非透析慢性肾衰竭患者、18例接受常规透析治疗的患者以及70例肾移植受者的α1 -抗胰蛋白酶和纤维蛋白原水平进行了研究。透析患者的α1 -抗胰蛋白酶和纤维蛋白原浓度最高，分别为314±98和485±127mg/dl。在肾移植受者中，发现α1 -抗胰蛋白酶和纤维蛋白原浓度之间存在显著正相关（p＜0.001）。高α1 -抗胰蛋白酶和纤维蛋白原水平似乎是潜在疾病或并发症引起的反应性过程的可能结果。我们的结果似乎表明，α1 -抗胰蛋白酶和纤维蛋白原均可归类为“急性期蛋白”。
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