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急性前葡萄膜炎与产气克雷伯菌:一种因果关系?

Acute anterior uveitis and Klebsiella aerogenes: a casual relationship?

作者信息

Willshaw H E

出版信息

Br J Ophthalmol. 1981 Nov;65(11):796-7. doi: 10.1136/bjo.65.11.796.

Abstract

This study was undertaken to investigate the hypothesis that episodes of anterior uveitis in patients with the HLA B27 antigen are triggered by the presence of Klebsiella aerogenes in the gastrointestinal tract. Forty patients were examined. While the recovery of klebsiella was greater in B27 positive patients with uveitis, the differences failed to reach statistical significance. The clinical state of patients with Klebsiella aerogenes in their faeces did not differ from that in whom klebsiella could not be recovered.

摘要

本研究旨在调查以下假设

HLA B27抗原阳性患者的前葡萄膜炎发作是由胃肠道中肺炎克雷伯菌的存在所引发的。对40名患者进行了检查。虽然葡萄膜炎的B27阳性患者中肺炎克雷伯菌的检出率更高,但差异未达到统计学意义。粪便中存在肺炎克雷伯菌的患者的临床状态与未检出该菌的患者并无差异。

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本文引用的文献

1
GENETIC BASIS OF SUSCEPTIBILITY TO VIRAL LEUKAEMOGENESIS.病毒致白血病易感性的遗传基础。
Lancet. 1964 Dec 5;2(7371):1207-9. doi: 10.1016/s0140-6736(64)91043-8.
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HL-A, immune-response genes, and disease.人类白细胞抗原、免疫反应基因与疾病
Lancet. 1974 Jun 22;1(7869):1269-75. doi: 10.1016/s0140-6736(74)90021-x.
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Ankylosing spondylitis and HL-A 27.强直性脊柱炎与人类白细胞抗原27
Lancet. 1973 Apr 28;1(7809):904-7. doi: 10.1016/s0140-6736(73)91360-3.
8
HL-A 27 and acute anterior uveitis.人类白细胞抗原A27与急性前葡萄膜炎
Br J Ophthalmol. 1975 May;59(5):270-5. doi: 10.1136/bjo.59.5.270.
9
Ankylosing spondylitis: klebsiella and HL-A B27.强直性脊柱炎:克雷伯菌与人类白细胞抗原B27
Rheumatol Rehabil. 1977 Aug;16(3):190-6. doi: 10.1093/rheumatology/16.3.190.

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