Dohmen J P, Lemmens J A, Lamers J J
Diagn Imaging. 1981;50(6):305-8.
A double-blind comparison of two recently introduced cholangiocholecystographic agents was carried out in 80 patients. Both agents proved to be equally effective in opacifying the gall-bladder and the bile ducts. The visualization of the bile ducts after cholecystectomy was slightly better after meglumine iotroxate administration. Both agents showed evidence of hepatic toxicity in mild or moderate degree. However, there were 3 cases in which adverse hepatotoxic reactions t meglumine iodoxamate have been observed. Careful observation of patients receiving this drug is advised.
对80名患者进行了两种最近推出的胆管胆囊造影剂的双盲比较。两种造影剂在使胆囊和胆管显影方面均证明同样有效。胆囊切除术后,静脉注射碘曲仑后胆管的显影略好。两种造影剂均显示出轻度或中度肝毒性迹象。然而,有3例观察到对碘番酸的不良肝毒性反应。建议对接受这种药物的患者进行仔细观察。