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[血清胃蛋白酶原:作为基础胃酸分泌和刺激胃酸分泌指标的价值(作者译)]

[Serum pepsinogen: its value as index of basal and stimulated gastric acid secretion (author's transl)].

作者信息

Florent C, Aymes C, Hirsch-Marie H, Rambaud J C

出版信息

Nouv Presse Med. 1982 Jan 9;11(1):35-7.

PMID:7036088
Abstract

Group I pepsinogen serum levels (PG I) and gastric acid outputs were determined before ("basal") and after pentagastrin or insulin stimulation in 13 patients with active duodenal ulcer and in 4 patients with hyperselective vagotomy. There was a statistically significant correlation between basal PG I serum level and basal acid output (r = 0,88, p less than 0,01) and between PG I serum level 45 min after stimulation and peak acid output (r = 0,68, p less than 0,01). However, the scattering of individual values was such that serum PG I cannot be used as an index of gastric acid secretion in clinical practice.

摘要

对13例活动性十二指肠溃疡患者和4例高选择性迷走神经切断术患者,在五肽胃泌素或胰岛素刺激前后分别测定了I组胃蛋白酶原血清水平(PG I)和胃酸分泌量。基础PG I血清水平与基础胃酸分泌量之间存在统计学显著相关性(r = 0.88,p < 0.01),刺激后45分钟的PG I血清水平与胃酸分泌峰值之间也存在相关性(r = 0.68,p < 0.01)。然而,个体值的离散程度使得血清PG I在临床实践中不能用作胃酸分泌的指标。

相似文献

1
[Serum pepsinogen: its value as index of basal and stimulated gastric acid secretion (author's transl)].[血清胃蛋白酶原:作为基础胃酸分泌和刺激胃酸分泌指标的价值(作者译)]
Nouv Presse Med. 1982 Jan 9;11(1):35-7.
2
Serum group I pepsinogens after consecutive stimulations with insulin and pentagastrin in unoperated duodenal ulcer patients and in duodenal ulcer patients after proximal gastric vagotomy.未手术的十二指肠溃疡患者以及近端胃迷走神经切断术后的十二指肠溃疡患者在接受胰岛素和五肽胃泌素连续刺激后的血清I组胃蛋白酶原。
Scand J Gastroenterol. 1984 Jan;19(1):52-5.
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Serum group I pepsinogens in unoperated duodenal ulcer patients and in duodenal ulcer patients after proximal gastric vagotomy.未接受手术的十二指肠溃疡患者及近端胃迷走神经切断术后十二指肠溃疡患者的血清I组胃蛋白酶原
Scand J Gastroenterol. 1983 May;18(3):397-9. doi: 10.3109/00365528309181613.
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Effect of proximal gastric vagotomy on serum pepsinogen I and II concentrations and acid secretion in duodenal ulcer patients.近端胃迷走神经切断术对十二指肠溃疡患者血清胃蛋白酶原I和II浓度及胃酸分泌的影响。
Dig Dis Sci. 1988 Jul;33(7):824-7. doi: 10.1007/BF01550970.
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[A global study of gastric secretion in duodenal ulcers: gastrin, pepsinogen and acid secretion].[十二指肠溃疡胃分泌的全球研究:胃泌素、胃蛋白酶原和胃酸分泌]
Rev Esp Enferm Dig. 1995 Jul;87(7):491-7.
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[Gastric acidity and serum levels of pepsinogen I and gastrin in children with primary duodenal ulcer].[原发性十二指肠溃疡患儿的胃酸及血清胃蛋白酶原I和胃泌素水平]
An Esp Pediatr. 1983 Nov;19(5):379-82.
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Serum group I pepsinogens during insulin and pentagastrin tests in unoperated and vagotomized duodenal ulcer patients.未手术及迷走神经切断术后十二指肠溃疡患者在胰岛素和五肽胃泌素试验期间的血清I型胃蛋白酶原
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Effect of proximal gastric vagotomy on insulin- induced gastric H+ and pepsin secretion and serum group I pepsinogens.近端胃迷走神经切断术对胰岛素诱导的胃H⁺和胃蛋白酶分泌以及血清I组胃蛋白酶原的影响。
Scand J Gastroenterol. 1982 Jun;17(4):555-9. doi: 10.3109/00365528209182249.
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Serum pepsinogen I levels: assessment of gastric acid secretion?血清胃蛋白酶原I水平:胃酸分泌的评估?
Prog Clin Biol Res. 1985;173:139-46.
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Food and pentagastrin stimulation of gastrin, pepsinogen I and acid in children with primary duodenal ulcer.原发性十二指肠溃疡患儿中食物和五肽胃泌素对胃泌素、胃蛋白酶原I及胃酸的刺激作用
Int J Tissue React. 1983;5(4):407-10.

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