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用遗传学方法解决兔中区分兔白细胞抗原(RLA)和引发皮肤反应性移植抗体的抗原的问题。

Genetic approach to the problem of distinction between RLA and antigens eliciting skin reacting transplantation antibodies in the rabbit.

作者信息

Kosiński S

出版信息

Arch Immunol Ther Exp (Warsz). 1981;29(4):455-9.

PMID:7036934
Abstract

This paper is a continuation of the previous study on the relationship between rabbit antigens eliciting skin reacting transplantation antibodies (SRTA) and histocompatibility RLA antigens. In this study two groups of families were tested. In the first one, antigenic phenotypes were typed using sera defined during investigation of random population as anti-RLA 1, RLA 2 and anti-RLA 3 and sera defined as SRTA anti-A and anti-B. In the second group - the sera prepared by intrafamilial immunization were applied. In both groups of families independent segregation of RLA and antigens eliciting SRTA was found. It supports the hypothesis about the distinction between these two antigenic systems.

摘要

本文是先前关于引发皮肤反应移植抗体(SRTA)的兔抗原与组织相容性RLA抗原之间关系研究的延续。在本研究中,对两组家系进行了检测。在第一组中,使用在随机人群调查期间定义的血清作为抗RLA 1、RLA 2和抗RLA 3以及定义为SRTA抗A和抗B的血清来确定抗原表型。在第二组中,应用通过家族内免疫制备的血清。在两组家系中均发现RLA和引发SRTA的抗原独立分离。这支持了关于这两种抗原系统存在差异的假说。

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