Synergistic interaction between UV and ionizing radiation in wild-type Schizosaccharomyces pombe.
作者信息
Gentner N E, Werner M M
出版信息
Mol Gen Genet. 1978 Aug 4;164(1):31-7. doi: 10.1007/BF00267595.
PMID:703759
Abstract
A synergistic effect of combined UV and gamma-ray exposure was observed for inactivation of wild-type Schizosaccharomyces pombe. A recombinational repair process, known to be important in restitution of damage induced by both radiations, appears to be involved; a radiation-sensitive mutant defective in this repair pathway showed essentially no synergistic interaction between UV and gamma-rays. Recovery from the synergistic effect of pre-exposure in wild-type cells did not display the expected fast gamma-recovery and slow UV-recovery kinetics previously observed for regain of resistance to further exposure to the same radiation. Rather, UV-irradiated cells recovered quickly from synergistic inactivation on subsequent gamma-exposure, while gamma-irradiated cells recovered UV-resistance slowly. Recovery from synergism thus appears to reflect the nature of the second, and not the initial, radiation.
摘要
相似文献
1
Synergistic interaction between UV and ionizing radiation in wild-type Schizosaccharomyces pombe.
Mol Gen Genet. 1978 Aug 4;164(1):31-7. doi: 10.1007/BF00267595.
2
Slow UV-recovery and fast gamma-recovery in wild-type Schizosaccharomyces pombe.
Mol Gen Genet. 1977 Jul 20;154(2):123-8. doi: 10.1007/BF00330827.
3
Effect of protein synthesis inhibition on recovery of UV- and gamma-irridated Schizosaccharomyces pombe from repair inhibition by caffeine.
Mol Gen Genet. 1976 Apr 23;145(1):1-5. doi: 10.1007/BF00331550.
4
Evidence for second "prereplicative G2" repair mechanism, specific for gamma-induced damage, in wild-type Schizosaccharomyces pombe.野生型粟酒裂殖酵母中存在针对γ射线诱导损伤的第二种“复制前G2期”修复机制的证据。
Mol Gen Genet. 1977 Jul 20;154(2):129-33. doi: 10.1007/BF00330828.
5
Both caffeine-induced lethality and the negative liquid holding effect, in UV- or gamma-irradiated wild-type Schizosaccharomyces pombe, are consequences of interference with a recombinational repair process.在紫外线或γ射线辐照的野生型粟酒裂殖酵母中，咖啡因诱导的致死性和负持液效应都是干扰重组修复过程的结果。
Mol Gen Genet. 1981;181(3):283-7. doi: 10.1007/BF00425598.
6
Contribution of a caffeine-sensitive recombinational repair pathway to survival and mutagenesis in UV-irradiated Schizosaccharomyces pombe.
Mol Gen Genet. 1978 Nov 16;167(1):43-9. doi: 10.1007/BF00270320.
7
Spontaneous and UV-induced recombination in radiation-sensitive mutants of Schizosaccharomyces pombe.粟酒裂殖酵母辐射敏感突变体中的自发重组和紫外线诱导重组
Mutat Res. 1981 Mar;81(1):37-48. doi: 10.1016/0027-5107(81)90085-3.
8
Mutations induced by X-radiation in the yeast Schizosaccharomyces pombe.
Mutat Res. 1975 May;28(2):163-73. doi: 10.1016/0027-5107(75)90093-7.
9
Temperature-sensitive mutant of Schizosaccharomyces pombe exhibiting enhanced radiation sensitivity.粟酒裂殖酵母的温度敏感突变体表现出增强的辐射敏感性。
J Bacteriol. 1976 Nov;128(2):536-9. doi: 10.1128/jb.128.2.536-539.1976.
10
Genetic control of radiation sensitivity in Schizosaccharomyces pombe.粟酒裂殖酵母辐射敏感性的遗传控制
Genetics. 1975 Apr;79(4):573-82. doi: 10.1093/genetics/79.4.573.
引用本文的文献
1
Combined Radiations: Biological Effects of Mixed Exposures Across the Radiation Spectrum.联合辐射：辐射谱混合暴露的生物学效应。
Biomolecules. 2025 Sep 5;15(9):1282. doi: 10.3390/biom15091282.
2
Differential Effects of Cold Atmospheric Plasma in the Treatment of Malignant Glioma.冷大气等离子体治疗恶性胶质瘤的差异效应
PLoS One. 2015 Jun 17;10(6):e0126313. doi: 10.1371/journal.pone.0126313. eCollection 2015.
3
Both caffeine-induced lethality and the negative liquid holding effect, in UV- or gamma-irradiated wild-type Schizosaccharomyces pombe, are consequences of interference with a recombinational repair process.在紫外线或γ射线辐照的野生型粟酒裂殖酵母中，咖啡因诱导的致死性和负持液效应都是干扰重组修复过程的结果。
Mol Gen Genet. 1981;181(3):283-7. doi: 10.1007/BF00425598.
4
The Saccharomyces cerevisiae RAD2 gene complements a Schizosaccharomyces pombe repair mutation.酿酒酵母RAD2基因可弥补粟酒裂殖酵母的修复突变。
Curr Genet. 1989 Jan;15(1):27-30. doi: 10.1007/BF00445748.
本文引用的文献
1
2
Similarity of repair of ionizing and ultra-violet radiation damage in Micrococcus radiodurans.耐辐射微球菌中电离辐射损伤与紫外线辐射损伤修复的相似性
Nature. 1965 Apr 24;206(982):373-5. doi: 10.1038/206373a0.
3
A UV-supersensitive mutant in the yeast Schizosaccharomyces pombe.粟酒裂殖酵母中的一个紫外线超敏突变体。
Mol Gen Genet. 1971;110(2):134-43. doi: 10.1007/BF00332644.
4
UV-sensitivity of the wild-type and different UVS mutants of Schizosaccharomyces pombe.粟酒裂殖酵母野生型及不同紫外线敏感（UVS）突变体的紫外线敏感性
Mutat Res. 1970 Nov;10(5):415-26. doi: 10.1016/0027-5107(70)90002-3.
5
Relation between repair mechanisms and induced mitotic recombination after UV irradiation, in the yeast Schizosaccharomyces pombe. Effects of caffeine.粟酒裂殖酵母中紫外线照射后修复机制与诱导的有丝分裂重组之间的关系。咖啡因的影响。
Mol Gen Genet. 1972;117(2):153-66. doi: 10.1007/BF00267612.
6
Interaction of x-ray and ultraviolet ray in killing cells.
Nature. 1968 Jun 15;218(5146):1077-8. doi: 10.1038/2181077a0.
7
8
The U.V.-x-ray synergism in Escherichia coli B-r. I. Inhibition by the incorporation of 5-bromouracil and by purine starvation.
Photochem Photobiol. 1972 Nov;16(5):459-64. doi: 10.1111/j.1751-1097.1972.tb06314.x.
9
The synergistic action of ultraviolet and x radiation on mutants of Escherichia coli K-12.紫外线与X射线对大肠杆菌K - 12突变体的协同作用。
Photochem Photobiol. 1973 Jul;18(1):1-8. doi: 10.1111/j.1751-1097.1973.tb06385.x.
10
Effects of radiation on polynucleotides.辐射对多核苷酸的影响。
Annu Rev Biophys Bioeng. 1972;1:293-346. doi: 10.1146/annurev.bb.01.060172.001453.
Zotero 插件