Warden G D, Saffle J R, Kravitz M
J Trauma. 1982 Feb;22(2):98-103. doi: 10.1097/00005373-198202000-00004.
While the technique of early excision and grafting has many advantages in the treatment of thermal injuries, it is not without significant complications. Hemorrhage accompanying burn wound excision can be deceptively great, as can the metabolic stress of large surgical procedures performed in the postburn period. In an effort to minimize these complications, we have developed a two-stage technique for excision and grafting of burn wounds. This technique employs layered excision of eschar, followed by an overnight stabilization period for restoration of normal body temperature and blood volume. Continuous soaking of excised areas promotes hemostasis, and insures a viable base for autografting performed on the following day. During 1978-1979, 117 burn patients underwent 137 two-stage excision and grafting procedures. Mean graft size was 1,988 cm2. Eighty-two per cent of the patients had all necessary grafting performed in a single two-stage operation, including grafts as large as 5,700 cm2. No graft loss occurred as a result of graft hematoma formation. Mean blood loss calculated for each two-stage operation was 2,627 cc, one third of which resulted from the harvesting of autografts. Temperature decrease during surgery was also great, with significant hypothermia occurring in 51% of procedures exceeding 2 hours in length. We conclude that performing excision and grafting in two stages limits hemorrhage and heat loss from each individual surgery, thereby permitting the performance of larger procedures. Nonetheless, continued awareness of the magnitude of these complications remains an essential of successful excisional therapy.
虽然早期切除与植皮技术在治疗热烧伤方面有诸多优势,但并非没有严重并发症。烧伤创面切除时伴随的出血可能看似量少实则量大,烧伤后进行大型外科手术时的代谢应激情况同样如此。为尽量减少这些并发症,我们研发了一种烧伤创面切除与植皮的两阶段技术。该技术采用分层切除焦痂,随后有一个过夜稳定期以恢复正常体温和血容量。对切除区域持续浸泡可促进止血,并确保次日进行自体植皮时有一个存活的基底。在1978 - 1979年期间,117例烧伤患者接受了137次两阶段切除与植皮手术。平均植皮面积为1988平方厘米。82%的患者在单次两阶段手术中完成了所有必要的植皮,包括面积达5700平方厘米的植皮。未因植皮血肿形成而出现植皮丢失情况。每次两阶段手术计算出的平均失血量为2627立方厘米,其中三分之一是由于采集自体皮所致。手术期间体温下降也很明显,51%时长超过2小时的手术出现了显著的体温过低情况。我们得出结论,分两阶段进行切除与植皮可限制每次个体手术中的出血和热量损失,从而允许进行更大规模的手术。尽管如此,持续意识到这些并发症的严重程度仍是成功切除治疗的关键要素。