Goodwin C W, Maguire M S, McManus W F, Pruitt B A
J Trauma. 1983 Jun;23(6):510-7. doi: 10.1097/00005373-198306000-00012.
To examine the role of early excision and grafting in the preservation of maximal function of hands with deep dermal burns, we prospectively evaluated 164 burned hands in consecutively admitted patients (mean age, 29 years; mean burn size, 37% of body surface). All hands with burn depths of second degree, deep second degree, or third degree above the level of the tendons and joint capsules were assessed preoperatively, intraoperatively, and at discharge from the hospital. Patients were treated by excision and grafting in the first or second postburn week, by delayed grafting alone, or by allowing primary healing. Total active range of motion measurements were made on the day of discharge (mean, 64th postoperative day). Mean operative blood loss per hand was 1,270 ml. When all (alive and dead) patients undergoing early excision and grafting were examined by a binomial probability model, early surgery was shown to produce no adverse affect on survival. Excision and grafting of hands with deep dermal burns, whether early or late, offered no advantage over physical therapy and primary healing in maintaining hand function. Likewise, hands with more superficial burns responded equally to operative and nonoperative treatment. While early excision and grafting of hands with third-degree burns tended to produce poorer results than did initial nonoperative care and late grafting, the differences are just outside the range of significance. Early excision and grafting of selected third-degree injuries of the hands may be indicated in patients with small total body surface burns in order to shorten hospital stay. However, early surgical intervention in patients with massive burns should be directed toward area coverage, not toward hand excision.
为了研究早期切除与植皮对手部深度真皮烧伤后最大功能保留的作用,我们对连续收治患者的164只烧伤手进行了前瞻性评估(平均年龄29岁;平均烧伤面积为体表面积的37%)。对所有肌腱和关节囊水平以上二度、深二度或三度烧伤的手在术前、术中和出院时进行评估。患者在烧伤后第一周或第二周接受切除与植皮治疗、单纯延迟植皮治疗或任其一期愈合。在出院当天(平均为术后第64天)进行总主动活动度测量。每只手的平均术中失血量为1270毫升。当采用二项概率模型对所有接受早期切除与植皮治疗的患者(包括存活和死亡患者)进行检查时,结果显示早期手术对生存率没有不利影响。手部深度真皮烧伤的切除与植皮,无论早期还是晚期,在维持手部功能方面并不比物理治疗和一期愈合更具优势。同样,较浅度烧伤的手对手术和非手术治疗的反应相同。虽然三度烧伤手的早期切除与植皮往往比最初的非手术治疗和晚期植皮效果更差,但差异仅略超出显著范围。对于总体表面积烧伤较小的患者,为缩短住院时间,可能需要对选定的手部三度损伤进行早期切除与植皮。然而,对于大面积烧伤患者,早期手术干预应针对创面覆盖,而非手部切除。