Povey C
Can Vet J. 1982 Jan;23(1):15-21.
A parvovirus of canine origin, cultured in a feline kidney cell line, was inactivated with formalin. Three pilot serials were produced and three forms of finished vaccine (nonadjuvanted, single adjuvanted and double adjuvanted) were tested in vaccination and challenge trials. A comparison was also made with two inactivated feline panleukopenia virus vaccines, one of which has official approval for use in dogs. The inactivated canine vaccine in nonadjuvanted, adjuvanted or double adjuvanted form was immunogenic in 20 of 20 vaccinated dogs. The double adjuvanted vaccine is selected as the one of choice on the basis of best and most persistent seriological response.
一种源自犬类的细小病毒，在猫肾细胞系中培养，并用福尔马林灭活。制备了三个试验批次，并在疫苗接种和攻毒试验中测试了三种成品疫苗形式（无佐剂、单佐剂和双佐剂）。还与两种灭活猫泛白细胞减少症病毒疫苗进行了比较，其中一种已获官方批准可用于犬类。无佐剂、单佐剂或双佐剂形式的灭活犬用疫苗在20只接种疫苗的犬中有20只具有免疫原性。基于最佳和最持久的血清学反应，双佐剂疫苗被选为首选。
