Appel M J, Scott F W, Carmichael L E
Vet Rec. 1979 Aug 25;105(8):156-9. doi: 10.1136/vr.105.8.156.
A newly recognised canine parvo like virus was isolated from faeces of dogs with haemorrhagic enteritis. Cell cultures from several species were susceptible to it. Virus infected cells could be demonstrated by staining with fluorescent antibody reagents (prepared against canine virus or feline panleucopenia virus) or by haemagglutination with pig or rhesus monkey red blood cells. Inhibition of haemagglutination by specific antiserum prepared in specific-pathogen-free beagles provided a convenient method for viral identification. Experimental inoculation of specific-pathogen-free beagles resulted in elevated body temperatures and caused lymphopenia lasting one to three days. Feline panleucopenia virus vaccines protected dogs against challenge with virulent canine parvo-like virus.
一种新发现的犬细小病毒样病毒从患有出血性肠炎的犬粪便中分离出来。几种物种的细胞培养物对其敏感。病毒感染的细胞可用荧光抗体试剂（针对犬病毒或猫泛白细胞减少症病毒制备）染色或用猪或恒河猴红细胞进行血凝试验来证明。在无特定病原体的比格犬中制备的特异性抗血清对血凝的抑制作用为病毒鉴定提供了一种简便方法。对无特定病原体的比格犬进行实验性接种导致体温升高，并引起持续一至三天的淋巴细胞减少。猫泛白细胞减少症病毒疫苗可保护犬免受强毒犬细小病毒样病毒的攻击。
