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In vitro and in vivo efficacy of conjugates of daunomycin with anti-tumor antibodies.

作者信息

Arnon R, Sela M

出版信息

Immunol Rev. 1982;62:5-27. doi: 10.1111/j.1600-065x.1982.tb00387.x.

DOI:10.1111/j.1600-065x.1982.tb00387.x
PMID:7042540
Abstract
摘要

相似文献

1
In vitro and in vivo efficacy of conjugates of daunomycin with anti-tumor antibodies.柔红霉素与抗肿瘤抗体偶联物的体外和体内疗效
Immunol Rev. 1982;62:5-27. doi: 10.1111/j.1600-065x.1982.tb00387.x.
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Site-directed chemotherapy with a drug bound to anti-idiotypic antibody to a lymphoma cell-surface IgM.将与抗淋巴瘤细胞表面IgM独特型抗体结合的药物进行定点化疗。
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Proceedings: Daunomycin and adriamycin antitumor cell antibody conjugates.会议论文:柔红霉素和阿霉素抗肿瘤细胞抗体偶联物
Isr J Med Sci. 1975 Dec;11(12):1396.
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Eradication of murine lymphoma and melanoma cells by chlorambucil-antibody complexes.苯丁酸氮芥-抗体复合物对小鼠淋巴瘤和黑色素瘤细胞的根除作用。
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5
Fab dimers of antitumor immunoglobulins as covalent carriers of daunomycin.作为柔红霉素共价载体的抗肿瘤免疫球蛋白Fab二聚体。
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6
Daunomycin--immunoglobulin conjugates, uptake and activity in vitro.柔红霉素-免疫球蛋白结合物:体外摄取与活性
Eur J Cancer (1965). 1978 Nov;14(11):1213-20. doi: 10.1016/0014-2964(78)90227-x.
7
Antibodies as carriers for oncostatic materials.作为抑癌物质载体的抗体。
Recent Results Cancer Res. 1980;75:236-45. doi: 10.1007/978-3-642-81491-4_37.
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The covalent binding of daunomycin and adriamycin to antibodies, with retention of both drug and antibody activities.
Cancer Res. 1975 May;35(5):1175-81.
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The effect in vivo of chemotherapeutic drug--antibody conjugates in two murine experimental tumor systems.化疗药物-抗体偶联物在两种小鼠实验性肿瘤系统中的体内效应。
Int J Cancer. 1978 Jun 15;21(6):747-55. doi: 10.1002/ijc.2910210612.
10
Experimentally developed cellular resistance to daunomycin. Resistance mechanisms, the daunomycin-pump and cross resistance to adriamycin, vincristine and vinblastine.实验诱导的细胞对柔红霉素的耐药性。耐药机制、柔红霉素泵以及对阿霉素、长春新碱和长春花碱的交叉耐药性。
Acta Pathol Microbiol Scand Suppl. 1976(256 Suppl):3-80.

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Cytotoxic effect of anti-idiotype antibody-chlorambucil conjugates against human lymphoblastoid cells.抗独特型抗体-苯丁酸氮芥偶联物对人淋巴母细胞样细胞的细胞毒性作用。
Immunology. 1983 Sep;50(1):57-64.
6
Chemotherapy by intravenous administration of conjugates of daunomycin with monoclonal and conventional anti-rat alpha-fetoprotein antibodies.通过静脉注射柔红霉素与单克隆及传统抗大鼠甲胎蛋白抗体的偶联物进行化疗。
Proc Natl Acad Sci U S A. 1982 Dec;79(24):7896-9. doi: 10.1073/pnas.79.24.7896.
7
Specific in vitro and in vivo drug localisation to tumour cells using a hybrid-hybrid monoclonal antibody recognising both carcinoembryonic antigen (CEA) and vinca alkaloids.使用一种既识别癌胚抗原(CEA)又识别长春花生物碱的杂交-杂交单克隆抗体,实现药物在体外和体内对肿瘤细胞的特异性定位。
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The antileukemic efficacy of an immunotoxin composed of a monoclonal anti-Thy-1 antibody disulfide linked to the ribosome-inactivating protein gelonin.一种由与核糖体失活蛋白去糖链皂苷通过二硫键连接的单克隆抗Thy-1抗体组成的免疫毒素的抗白血病疗效。
Cancer Immunol Immunother. 1987;25(1):31-40. doi: 10.1007/BF00199298.
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Doxorubicin conjugates of monoclonal antibodies to hepatoma-associated antigens.肝癌相关抗原单克隆抗体的阿霉素缀合物。
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Antigen-specific drug-targeting used to manipulate an immune response in vivo.用于在体内操纵免疫反应的抗原特异性药物靶向。
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