Butlin R K, Collins P M, Skevington S J, Day T H
Heredity (Edinb). 1982 Feb;48(Pt 1):45-55. doi: 10.1038/hdy.1982.5.
Samples of the seaweed fly, Coelopa frigida, from six populations widely spaced around the English coast were collected during 1974-76 and again in 1979-80. Gene frequencies at the Alcohol dehydrogenase (Adh) locus were found not to vary significantly between sites, nor over the five year period of their study. Genotype distributions are compared with Hardy-Weinberg expectations and show consistent, mostly significant, differences. These results are interpreted in the light of an association between the Adh locus and a chromosomal inversion polymorphism. It is argued that the remarkable geographical uniformity must indicate the presence of strong selection, probably taking the form of heterokaryotypic advantage.
1974年至1976年以及1979年至1980年期间,采集了来自英国海岸周围六个分布广泛的群体的海草蝇(Coelopa frigida)样本。研究发现,乙醇脱氢酶(Adh)基因座的基因频率在不同地点之间以及在他们研究的五年期间均无显著差异。将基因型分布与哈迪-温伯格预期进行比较,结果显示出一致的、大多显著的差异。这些结果根据Adh基因座与染色体倒位多态性之间的关联进行了解释。有人认为,显著的地理一致性必定表明存在强烈的选择,可能采取异核型优势的形式。