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莱姆病——一种蜱传播的螺旋体病?

Lyme disease-a tick-borne spirochetosis?

作者信息

Burgdorfer W, Barbour A G, Hayes S F, Benach J L, Grunwaldt E, Davis J P

出版信息

Science. 1982 Jun 18;216(4552):1317-9. doi: 10.1126/science.7043737.

Abstract

A treponema-like spirochete was detected in and isolated from adult Ixodes dammini, the incriminated tick vector of Lyme disease. Causally related to the spirochetes may be long-lasting cutaneous lesions that appeared on New Zealand White rabbits 10 to 12 weeks after infected ticks fed on them. Samples of serum from patients with Lyme disease were shown by indirect immunofluorescence to contain antibodies to this agent. It is suggested that the newly discovered spirochete is involved in the etiology of Lyme disease.

摘要

在成年达米尼硬蜱(Ixodes dammini)中检测到并分离出一种类似密螺旋体的螺旋体,达米尼硬蜱是莱姆病的致病蜱媒。与这些螺旋体可能存在因果关系的是,在新西兰白兔被感染蜱叮咬10至12周后出现的持久性皮肤损伤。通过间接免疫荧光法显示,莱姆病患者的血清样本中含有针对这种病原体的抗体。有人提出,新发现的螺旋体与莱姆病的病因有关。

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