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从两名莱姆病患者血液中分离出的螺旋体。

Spirochetes isolated from the blood of two patients with Lyme disease.

作者信息

Benach J L, Bosler E M, Hanrahan J P, Coleman J L, Habicht G S, Bast T F, Cameron D J, Ziegler J L, Barbour A G, Burgdorfer W, Edelman R, Kaslow R A

出版信息

N Engl J Med. 1983 Mar 31;308(13):740-2. doi: 10.1056/NEJM198303313081302.

DOI:10.1056/NEJM198303313081302
PMID:6828119
Abstract

We isolated spirochetes from the blood of 2 of 36 patients in Long Island and Westchester County, New York, who had signs and symptoms suggestive of Lyme disease. The spirochetes were morphologically similar and serologically identical to organisms recently found to infect lxodes dammini ticks, which are endemic to the area and have been epidemiologically implicated as vectors of Lyme disease. In both patients, there was a rise in specific antispirochetal antibodies in paired specimens of serum. We conclude that the l. dammini spirochete has an etiologic role in Lyme disease.

摘要

我们从纽约长岛和韦斯特切斯特县36名有莱姆病体征和症状的患者中的2人血液中分离出了螺旋体。这些螺旋体在形态上与最近发现感染达米尼硬蜱的微生物相似,血清学上也相同,达米尼硬蜱是该地区的地方种,在流行病学上被认为是莱姆病的传播媒介。在这两名患者中,配对血清标本中的特异性抗螺旋体抗体均有升高。我们得出结论,达米尼螺旋体在莱姆病中具有病因学作用。

相似文献

1
Spirochetes isolated from the blood of two patients with Lyme disease.从两名莱姆病患者血液中分离出的螺旋体。
N Engl J Med. 1983 Mar 31;308(13):740-2. doi: 10.1056/NEJM198303313081302.
2
The spirochetal etiology of Lyme disease.莱姆病的螺旋体病因
N Engl J Med. 1983 Mar 31;308(13):733-40. doi: 10.1056/NEJM198303313081301.
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Spirochete isolated in tick vectors of Lyme disease.在莱姆病的蜱传播媒介中分离出的螺旋体。
Hosp Pract (Off Ed). 1982 Aug;17(8):46, 54-5.
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Lyme disease in northern California.加利福尼亚北部的莱姆病。
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Spirochetes in Ixodes dammini and mammals from Connecticut.来自康涅狄格州的达氏硬蜱和哺乳动物体内的螺旋体。
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Antibodies to spirochetes in white-tailed deer and prevalence of infected ticks from foci of Lyme disease in Connecticut.康涅狄格州白尾鹿体内螺旋体抗体及莱姆病疫源地感染蜱虫的患病率
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Histologic demonstration of intradermal spirochetes in a patient with Lyme disease.莱姆病患者真皮内螺旋体的组织学证实。
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[Lyme disease: a new infectious disease].[莱姆病:一种新的传染病]
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